Results 121 to 130 of about 233,089 (385)
The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability
Cells, 2019 Chromosomal instability (CIN) is an intricate phenomenon that is often found in human cancer, characterized by persisting errors in chromosome segregation.
Christy Hong +2 more
doaj +1 more source
Cryogenic temperature effects on sting-balance deflections in the National Transonic Facility [PDF]
An investigation was conducted at the National Transonic Facility (NTF) to document the change in sting-balance deflections from ambient to cryogenic temperatures.
Adcock, Jerry B. +1 more
core +1 more source
Carbon Nanotube 3D Integrated Circuits: From Design to Applications
Advanced Functional Materials, EarlyView.As Moore's law approaches its physical limits, carbon nanotube (CNT) 3D integrated circuits (ICs) emerge as a promising alternative due to the miniaturization, high mobility, and low power consumption. CNT 3D ICs in optoelectronics, memory, and monolithic ICs are reviewed while addressing challenges in fabrication, design, and integration.
Han‐Yang Liu +3 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Geometric multi‐bit patterning based on dynamic wetting and dewetting phenomena creates roulette‐like Physical Unclonable Function (PUF) labels with stochastic yet deterministic properties. This method leverages the solutal‐Marangoni effect for high randomness while achieving deterministic multinary patterns through polygonal confinement of binary ...
Yeongin Cho +8 more
wiley +1 more source
Human Vaccines & Immunotherapeutics, 2018 Stimulator of interferon genes (STING) was defined as an important molecule for promoting antitumor immunity through mediating type I interferon (IFN) production by sensing its ligands such as cyclic GMP-AMP (cGAMP).
Takayuki Ohkuri +3 more
doaj +1 more source
Autonomous Control of Extrusion Bioprinting Using Convolutional Neural Networks
Advanced Functional Materials, EarlyView.This work presents a novel computer vision system for high‐fidelity monitoring of extrusion‐based bioprinting and a correction system utilizing convolutional neural networks for error mitigation. This system has demonstrated high detection accuracy and extrusion correction abilities that advance the state of the art toward accelerated printing ...
Daniel Kelly +4 more
wiley +1 more source
cGAS-independent STING activation in response to DNA damage
Molecular & Cellular Oncology, 2019 Self-DNA has previously been thought to be protected from immune detection by compartmentalisation in the nucleus or mitochondria. Here, we describe the discovery of a signalling cascade that links the detection of DNA damage in the nucleus to the ...
Leonie Unterholzner, Gillian Dunphy
doaj +1 more source
STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death [PDF]
, 2019 STING gain-of-function mutations cause lung disease and T cell cytopenia through unknown mechanisms. Here, we found that these mutants induce chronic activation of ER stress and unfolded protein response (UPR), leading to T cell death by apoptosis in ...
Chen, Yu-Ju +6 more
core +1 more source
Effect of sting size on the wake of a sphere at subcritical Reynolds numbers [PDF]
, 2008 Vortex shedding and turbulent motion in the wake of a sphere that is supported using a streamwise-aligned cylindrical sting are investigated at a subcritical Reynolds number of Re=3800, using high speed particle image velocimetry.
Achenbach E. +7 more
core +1 more source
Advanced Functional Materials, EarlyView.This study introduces a paper‐based biodegradable, humidity‐insensitive e‐nose for real‐time breath analysis, addressing challenges in existing technologies such as humidity interference, high costs, and environmental impact. Featuring hydrophobic polymer coatings, these sensors reliably detect VOCs even in high‐moisture environments.
Indrajit Mondal +2 more
wiley +1 more source