Results 171 to 180 of about 206,921 (307)

Protective and pathogenic: The Janus-faced role of cGAS-STING in the brain. [PDF]

J Cereb Blood Flow Metab
Corona C, Kanzlemar C, Hussaini A, Ratan RR.   +3 more
europepmc   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Monkeypox virus protein OPG188 antagonizes cGAS-STING antiviral signaling pathway to mediate immune evasion. [PDF]

Proc Natl Acad Sci U S A
Pan Z, Zhang S, Geng X, Wang N, Zhang L, Wang L, Yin C, Zhang H, Liu S, Zhang L, Fan J, Xue G, Li R, Li T, Yu Y, Yao H, Jin C, Wu N.   +17 more
europepmc   +1 more source

Structural Color Inkjet Printing With Mie‐Resonant Silicon Nanoparticles

Advanced Materials, EarlyView.
Water‐based inks incorporating Mie‐resonant silicon nanoparticles were developed, and their application to structural color inkjet printing was demonstrated. By controlling the nanoparticle size and concentration, coloration covering a wide color gamut was achieved.
Hiroto Yamana, Haruki Tanaka, Hiroshi Sugimoto, Minoru Fujii   +3 more
wiley   +1 more source

Jelly fish eye stings

Journal of the Egyptian Ophthalmological Society, 2016
Ahmad H Ahmad
doaj   +1 more source

<i>Gynostemma pentaphyllum</i>-derived extracellular vesicles alleviate skin aging by destabilizing STING. [PDF]

Bioact Mater
Wang D, Duan S, Fan Y, Chen T, Hao Y, Liang Y, Ni J, Wang X, Shen X, Cao G, You Y, Liu Z, Xia H.   +12 more
europepmc   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

Advanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj, Roshni Satheesh Babu, Yuxin Xia, Eva Bestelink, Radu Sporea, Nikos Hastas, Ioannis Zeimpekis, Dimitra G. Georgiadou, Sayani Majumdar   +8 more
wiley   +1 more source

Carnosic Acid Activates the STING/IRF3 Pathway to Induce Nitric Oxide-Mediated Apoptosis in Osteosarcoma Cells. [PDF]

Antioxidants (Basel)
Guo W, Yin L, Wu Q, Chu J.
europepmc   +1 more source

When Poor Exciton Dissociation Limits Photocurrents in Organic Solar Cells: Why Low Offset Non‐Fullerene Acceptor Blends Can't Be Efficient

Advanced Materials, EarlyView.
The energetic offset between the donor and the acceptor components in organic photoactive layers is central to the tradeoff between photovoltage and photocurrent losses. This Perspective covers the most important issues surrounding this topic in non‐fullerene acceptor blends, from the difficulty of accurately determining state energies and driving ...
Dieter Neher, Manasi Pranav
wiley   +1 more source

Astragalus Polysaccharides Induce Immunogenic Cell Death in Melanoma: A Mechanism Mediated by cGAS/STING Activation via Intratumoral Microbiota Modulation. [PDF]

Cancer Med
Qiao X, Ding G, Lu Q, Chen Y, Wang X, Wang Y, Ma J, Cheng X.   +7 more
europepmc   +1 more source