Results 211 to 220 of about 206,921 (307)

Calibrating the RT-cGAS-STING axis to drive cold-to-hot tumor transformation: mechanistic foundations and translational strategies for combination with immunotherapy. [PDF]

Mol Cancer
Kang YF, Chen JM, Xu BC, Xu JN, Qin Q, Wu HL, Wang J, Wang RK, Wu YR, Tang WJ, Zeng YC.   +10 more
europepmc   +1 more source

A WASP STING [PDF]

British Journal of Ophthalmology, 1944
openaire   +2 more sources

Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability

Advanced Materials Technologies, EarlyView.
ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann, Jessica Faber, Franz Moser, Alessandro Cianciosi, Nicoletta Murenu, Joachim Schenk, Katrin G. Heinze, Natascha Schaefer, Silvia Budday, Tomasz Jungst   +9 more
wiley   +1 more source

Structural and biochemical insights into the inhibition of <i>Mycobacterium tuberculosis</i> cyclic dinucleotide phosphodiesterase by a sulfur-modified cyclic dinucleotide analog. [PDF]

RSC Chem Biol
Hanuman DS, Neeharika S, Murari SK, Yeboah SK, Sintim HO, Rajakumara E.   +5 more
europepmc   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

A STING signaling relay from tumor cells to macrophages mediates the improved efficacy of combination chemotherapy in pancreatic cancer. [PDF]

J Biomed Sci
Ding H, Mao Y, Yao Z, Xing K, Yang Q, Wang R, Wang J, Liu Y, Guo H, Wang Z, Wang X, Wang J, Xue J, Li S, Xia X.   +14 more
europepmc   +1 more source

Hierarchical Multi‐Material Architectures With Gradient Design for Dynamic‐Range Flexible Tactile Sensing

Advanced Materials Technologies, EarlyView.
Hierarchical multi‐material TPMS lattices are engineered as flexible tactile sensors by combining soft and stiff elastomeric layers with a conformal conductive coating. The bilayer architecture delivers sensitivity at low pressures while maintaining a broad detectable range under large loads, enabling reliable pressure and vibration monitoring for ...
Reza Noroozi, Domenic Quiquero, Yan Yan Shery Huang, HaoTian Harvey Shi   +3 more
wiley   +1 more source

Emergency Department Presentations for Jellyfish Stings in Southern China: A Cross-Sectional Analysis of Pain Severity and Treatment Timing. [PDF]

J Pain Res
Li X, Wang H, Guo X, Huo C, Jiang M, Zhang J.   +5 more
europepmc   +1 more source

Low‐Temperature Processed Optoelectronic Synapses With Enhanced Responsivity for Edge‐Oriented In‐Sensor Reservoir Computing

Advanced Materials Technologies, EarlyView.
Image pixels are converted into optical pulse sequences to stimulate the optoelectronic synaptic device, generating dynamic responses that form high‐dimensional features. These features improve classification efficiency and demonstrate strong potential for neuromorphic edge computing systems.
Jo‐Lin Chen, Shi‐Qian Guo, Yu‐Chuan Chiu, Po‐Tsun Liu   +3 more
wiley   +1 more source

Interferon stimulatory DNA activates the DNA damage signaling through ATM and DNA-PK sensing. [PDF]

J Biol Chem
Kemiha S, Rejón-Franco L, Ghibaudo E, Eloiflin RJ, Chemarin M, Hawillo K, Laguette N, Técher H.   +7 more
europepmc   +1 more source