Results 331 to 340 of about 233,089 (385)

Recent Advances in Variable‐Stiffness Robotic Systems Enabled by Phase‐Change Materials

Advanced Robotics Research, EarlyView.
Phase‐change materials (PCMs), such as shape memory alloys, hydrogels, shape memory polymers, liquid crystal elastomers, and low‐melting‐point alloys, are driving advancements in stiffness‐tunable robotic systems across a wide range of applications. This review highlights recent progress in PCM‐enabled robotics, focusing on their underlying mechanisms,
Sukrit Gaira, Liao Wu, Ming Li, Priyank Kumar, Xiaopeng Li, Shi‐Yang Tang   +5 more
wiley   +1 more source

XMT-2056, a HER2-Directed STING Agonist Antibody-Drug Conjugate, Induces Innate Antitumor Immune Responses by Acting on Cancer Cells and Tumor-Resident Immune Cells. [PDF]

Clin Cancer Res
Bukhalid RA, Duvall JR, Lancaster K, Catcott KC, Malli Cetinbas N, Monnell T, Routhier C, Thomas JD, Bentley KW, Collins SD, Ditty E, Eitas TK, Kelleher EW, Shaw P, Soomer-James J, Ter-Ovanesyan E, Xu L, Zurita J, Toader D, Damelin M, Lowinger TB.   +20 more
europepmc   +1 more source

A Force Myography (FMG) Armband Based on Micro‐Structured Textile‐Pressure Sensors for Human‐Machine Interface (HMI)

Advanced Sensor Research, EarlyView.
This study introduces a textile‐based capacitive pressure sensor featuring a triangular prism microstructure, which significantly enhances sensitivity to 5.52% kPa−¹ and supports a wide sensing range up to 330 kPa. The sensor's performance is validated in a 4‐channel capacitive pressure‐based force myography (cFMG) armband for gesture recognition ...
Rayane Tchantchane, Hao Zhou, Shen Zhang, Gursel Alici   +3 more
wiley   +1 more source

Distinct oligomeric assemblies of STING induced by non-nucleotide agonists. [PDF]

Nat Commun
Gharpure A, Sulpizio A, Loeffler JR, Fernández-Quintero ML, Tran AS, Lairson LL, Ward AB.   +6 more
europepmc   +1 more source

Cost‐Effective Hierarchical Cobalt Nanostructured Laser‐Induced Graphene for Enhanced Uric Acid Detection

Advanced Sensor Research, EarlyView.
A one‐step electrochemical strategy is utilized to develop a flexible, enzyme‐free biosensor for the sensitive detection of uric acid (UA). The hierarchical cobalt nanostructures synergistically enhance the performance of the biosensor, resulting in a broad detection range of 5 to 700 µM with a sensitivity of 6.75 µA µM−1 cm−2 and a low detection limit
Anju Joshi, Gymama Slaughter
wiley   +1 more source

STING activation improves T-cell-engaging immunotherapy for acute myeloid leukemia.

Blood
Linder A, Nixdorf D, Kuhl N, Piseddu I, Xu T, Holtermann AV, Kuut G, Endres R, Philipp N, Bücklein V, de Graaff J, Carell T, Kobold S, Kischel R, Hornung V, Subklewe M.   +15 more
europepmc   +1 more source

Treatment with human placental extracts inhibits allergic rhinitis by modulating AMPK/SHP1/SHP2/STING signaling. [PDF]

Mol Med Rep
Wo B, Liu S, Liang Z, Li X.
europepmc   +1 more source

Towards Neural‐Network‐Based Optical Temperature Sensing of Semiconductor Membrane External Cavity Laser

Advanced Sensor Research, EarlyView.
Neural‐network‐based (NN) temperature sensing: Machine‐learning non‐contact method for the determination of the temperature of a laser gain medium via its laser emission with few‐layer neural net (NN) regression model. Training the feed‐forward NN with data recorded by compact micro‐spectrometers for both a diode pump laser and optically‐pumped gain ...
Jakob Mannstadt, Arash Rahimi‐Iman
wiley   +1 more source

Oral ENPP1 inhibitor designed using generative AI as next generation STING modulator for solid tumors. [PDF]

Nat Commun
Pu C, Cui H, Yu H, Cheng X, Zhang M, Qin L, Ning Z, Zhang W, Chen S, Qian Y, Wang F, Wang L, Lin X, Gennert D, Pun FW, Ren F, Zhavoronkov A.   +16 more
europepmc   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

Advanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak, Shivananda Kandagalla, Ramesh Sistla   +2 more
wiley   +1 more source