Results 31 to 40 of about 236,502 (262)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Energies, 2020 Increasing the popularity of electric vehicles is one way of reducing greenhouse gas emissions and making the economy more sustainable. In Poland, the use of electric vehicles is to be increased by the adoption of the Act on Electromobility and ...
Paweł Ziemba
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Weighted Chernoff Information and Optimal Loss Exponent in Context-Sensitive Hypothesis Testing
EntropyWe study binary hypothesis testing for i.i.d. observations under a multiplicative context weight. For the optimal weighted total loss, defined as the sum of weighted type-I and type-II losses, we prove the logarithmic asymptotic Ln∗=exp{−nDCw(P,Q)+o(n ...
Mark Kelbert, El’mira Yu. Kalimulina
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Branching Random Walks in a Random Killing Environment with a Single Reproduction Source
MathematicsWe consider a continuous-time branching random walk on Z in a random non-homogeneous environment. The process starts with a single particle at initial time t=0.
Vladimir Kutsenko +2 more
doaj +1 more source
Stochastic Finite Element Analysis of Root-Reinforcement Effects in Long and Steep Slopes
Geotechnics, 2023 This article introduces a novel numerical scheme within the finite element method (FEM) to study soil heterogeneity, specifically focusing on the root–soil matrix in fracture treatments.
Ram Chandra Tiwari +1 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source