Results 51 to 60 of about 3,659,418 (206)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Controllability of Nonlinear Neutral Stochastic Differential Inclusions with Infinite Delay [PDF]

Mathematical Problems in Engineering, 2013
The paper is concerned with the controllability of nonlinear neutral stochastic differential inclusions with infinite delay in a Hilbert space. Sufficient conditions for the controllability are obtained by using a fixed-point theorem for condensing maps due to O'Regan.
Li, Yong, Zou, Qiang
openaire   +2 more sources

Stochastic representation of partial differential inclusions

Journal of Mathematical Analysis and Applications, 2009
Partial differential inclusions of the form \(u_t^\prime \in \mathbb L _{FG}u+cu\) and \(\psi \in \mathbb L_{FG}u+cu\), where \(\mathbb L_{FG}\) is a uniformly parabolic second order set-valued operator, are considered. In particular, based on diffusions properties of weak solutions to stochastic differential inclusions, some existence and ...
openaire   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Solvability and optimal feedback control for stochastic switched non-autonomous differential inclusion with deviated arguments

Systems Science & Control Engineering
This article is concerned with studying the solvability and optimal feedback control for stochastic switched non-autonomous differential inclusion with deviated arguments and fractional Brownian motion in Hilbert spaces.
Nageshwari Sivakumar, Durga Nagarajan
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Extensive Alternative Splicing of KIR Transcripts

Frontiers in Immunology, 2018
The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules.
Jesse Bruijnesteijn, Marit K. H. van der Wiel, Nanine de Groot, Nel Otting, Annemiek J. M. de Vos-Rouweler, Neubury M. Lardy, Natasja G. de Groot, Ronald E. Bontrop, Ronald E. Bontrop   +8 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Effects of fractional derivative and Wiener process on approximate boundary controllability of differential inclusion

Boundary Value Problems
One of the core concepts of contemporary control theory is the idea that a dynamical system can be controlled. Several abstract settings have been developed to describe the distributed control systems in a domain in which the control is acted through the
Noorah Mshary, Hamdy M. Ahmed, Ahmed S. Ghanem   +2 more
doaj   +1 more source