Results 61 to 70 of about 16,327 (277)

Solvability and optimal feedback control for stochastic switched non-autonomous differential inclusion with deviated arguments

open access: yesSystems Science & Control Engineering
This article is concerned with studying the solvability and optimal feedback control for stochastic switched non-autonomous differential inclusion with deviated arguments and fractional Brownian motion in Hilbert spaces.
Nageshwari Sivakumar, Durga Nagarajan
doaj   +1 more source

Extensive Alternative Splicing of KIR Transcripts

open access: yesFrontiers in Immunology, 2018
The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules.
Jesse Bruijnesteijn   +8 more
doaj   +1 more source

Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese Zucker Rats [PDF]

open access: yes, 2015
Inclusion of stochastic differential equations in mixed effects models provides means to quantify and distinguish three sources of variability in data. In addition to the two commonly encountered sources, measurement error and interindividual variability,
Leander, Jacob   +15 more
core   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Numerical approximation of Backward Stochastic Differential Equations with Jumps [PDF]

open access: yes, 2014
In this paper we propose a numerical method to approximate the solution of a Backward Stochastic Differential Equations with Jumps (BSDEJ). This method is based on the construction of a discrete BSDEJ driven by a complete system of three orthogonal ...
Mordecki, Ernesto   +2 more
core  

Stabilized Numerical Methods for Stochastic Differential Equations driven by Diffusion and Jump-Diffusion Processes [PDF]

open access: yes, 2015
Stochastic models that account for sudden, unforeseeable events play a crucial role in many different fields such as finance, economics, biology, chemistry, physics and so on.
Blumenthal, Adrian
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Effects of fractional derivative and Wiener process on approximate boundary controllability of differential inclusion

open access: yesBoundary Value Problems
One of the core concepts of contemporary control theory is the idea that a dynamical system can be controlled. Several abstract settings have been developed to describe the distributed control systems in a domain in which the control is acted through the
Noorah Mshary   +2 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

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