Results 41 to 50 of about 108,723 (292)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Andrzej Lasota's selected results [PDF]

open access: yesOpuscula Mathematica, 2008
In this article we recall Andrzej Lasota's selected results which either indicated new directions of research, or layed the foundations for new approaches, or solved interesting problems. The area of mathematical interests of Professor Andrzej Lasota was
Józef Myjak
doaj  

Pullback attractors of nonautonomous and stochastic multivalued dynamical systems [PDF]

open access: yes, 2003
In this paper we study the existence of pullback global attractors for multivalued processes generated by differential inclusions. First, we define multivalued dynamical processes, prove abstract results on the existence of !-limit sets and global ...
Caraballo Garrido, Tomás   +3 more
core  

Hilfer Fractional Neutral Stochastic Differential Inclusions with Clarke’s Subdifferential Type and fBm: Approximate Boundary Controllability

open access: yesContemporary Mathematics
In this paper, the approximate boundary controllability of Hilfer fractional neutral stochastic differential inclusions with fractional Brownian motion (fBm) and Clarke’s subdifferential in Hilbert space is discussed.
K. Nandhaprasadh, R. Udhayakumar
semanticscholar   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Two Timescale Stochastic Approximation with Controlled Markov noise and Off-policy temporal difference learning

open access: yes, 2017
We present for the first time an asymptotic convergence analysis of two time-scale stochastic approximation driven by `controlled' Markov noise. In particular, both the faster and slower recursions have non-additive controlled Markov noise components in ...
Bhatnagar, Shalabh, Karmakar, Prasenjit
core   +1 more source

Remarks on Differential Inclusion limits of Stochastic Approximation

open access: yes, 2023
For stochastic approximation algorithms with discontinuous dynamics, it is shown that under suitable distributional assumptions, the interpolated iterates track a Fillipov solution of the limiting differential inclusion. In addition, we give an alternative control theoretic approach to recent results of [7] on certain limiting empirical measures ...
Borkar, Vivek, Shah, Dhruv
openaire   +2 more sources

Controllability of Nonlinear Neutral Stochastic Differential Inclusions with Infinite Delay [PDF]

open access: yesMathematical Problems in Engineering, 2013
The paper is concerned with the controllability of nonlinear neutral stochastic differential inclusions with infinite delay in a Hilbert space. Sufficient conditions for the controllability are obtained by using a fixed-point theorem for condensing maps due to O'Regan.
Li, Yong, Zou, Qiang
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Stochastic representation of partial differential inclusions

open access: yesJournal of Mathematical Analysis and Applications, 2009
Partial differential inclusions of the form \(u_t^\prime \in \mathbb L _{FG}u+cu\) and \(\psi \in \mathbb L_{FG}u+cu\), where \(\mathbb L_{FG}\) is a uniformly parabolic second order set-valued operator, are considered. In particular, based on diffusions properties of weak solutions to stochastic differential inclusions, some existence and ...
openaire   +1 more source

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