Results 51 to 60 of about 1,529 (261)
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
On differential equations and inclusions with mean derivatives on a compact manifold [PDF]
, 2007 We introduce and investigate a new sort of stochastic differential inclusions on manifolds, given in terms of mean derivatives of a stochastic process, introduced by Nelson for the needs of the so called stochastic mechanics.
Azarina, S., Gliklikh, Yu.
core +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
EXISTENCE RESULTS ON IMPULSIVE STOCHASTIC FUNCTIONAL DIFFERENTIAL INCLUSIONS WITH DELAYS [PDF]
, 2020 . This article presents the results on existence of mild solutions for impulsive stochastic differential inclusions under sufficient conditions.
A Vinodkumar, A Anguraj, Y K Chang
core
Existence of solutions for second order stochastic differential inclusions in Hilbert spaces [PDF]
, 2007 In this paper, sufficient conditions are given for the existence of solutions for a class of second order stochastic differential inclusions in Hilbert space with the help of Leray-Schauder Nonlinear ...
Balasubramaniam, P., Ntouyas, S.
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
(SI10-083) Approximate Controllability of Infinite-delayed Second-order Stochastic Differential Inclusions Involving Non-instantaneous Impulses [PDF]
, 2022 This manuscript investigates a broad class of second-order stochastic differential inclusions consisting of infinite delay and non-instantaneous impulses in a Hilbert space setting. We first formulate a new collection of sufficient conditions that ensure
Yadav, Shobha, Kumar, Surendra
core +1 more source
Advanced Engineering Materials, EarlyView.Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source
What Do Large Language Models Know About Materials?
Advanced Engineering Materials, EarlyView.If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer +2 more
wiley +1 more source