Results 171 to 180 of about 142,362 (315)

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

A Geometric Interpretation of Stochastic Gradient Descent Using Diffusion Metrics. [PDF]

Entropy (Basel), 2020
Fioresi R, Chaudhari P, Soatto S.
europepmc   +1 more source

Unforgeability in Stochastic Gradient Descent

Proceedings of the 2023 ACM SIGSAC Conference on Computer and Communications Security, 2023
Teodora Baluta, Ivica Nikolic, Racchit Jain, Divesh Aggarwal, Prateek Saxena   +4 more
openaire   +1 more source

Almost Bayesian: The Fractal Dynamics of Stochastic Gradient Descent [PDF]

Max Hennick, Stijn De Baerdemacker
openalex   +1 more source

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

Advanced Science, EarlyView.
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang, Yuxin Yang, William Martin, Kingsten Lin, Zixu Wang, Cheng‐Chang Lu, Weiwen Jiang, Ruth Nussinov, Joseph Loscalzo, Qiang Guan, Feixiong Cheng   +10 more
wiley   +1 more source

Parallel Stochastic Gradient Descent with Sound Combiners [PDF]

, 2017
Saeed Maleki, Madanlal Musuvathi, Todd Mytkowicz   +2 more
openalex   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

SSGD: SPARSITY-PROMOTING STOCHASTIC GRADIENT DESCENT ALGORITHM FOR UNBIASED DNN PRUNING. [PDF]

Proc IEEE Int Conf Acoust Speech Signal Process, 2020
Lee CH, Fedorov I, Rao BD, Garudadri H.
europepmc   +1 more source

Initial Distance‐Dependent Mean Force Drives Synaptic Vesicle Motion Toward Fusion Sites in Stimulated Hippocampal Neurons

Advanced Science, EarlyView.
Synaptic vesicle (SV) motion and exocytosis dynamics in the presynaptic terminals of live neurons are intimately linked to synaptic transmission during neuronal activity. In this work, it is revealed that, during electrical stimulation, SVs located farther from their fusion sites exhibit greater straightness and experience larger mean forces directed ...
Gyunam Park, Ji‐Hyun Kim, Hunki Lee, Chungwon Park, Sidong Chen, Luke Bates, Jaeyoung Sung, Hyokeun Park   +7 more
wiley   +1 more source

Mutual Information Based Learning Rate Decay for Stochastic Gradient Descent Training of Deep Neural Networks. [PDF]

Entropy (Basel), 2020
Vasudevan S.
europepmc   +1 more source