Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang +12 more
wiley +1 more source
On the Stochastic Dynamics for the Regularized Kappa-Distributed Plasmas. [PDF]
Guo R.
europepmc +1 more source
Wide‐Range Adaptive Metal Oxide for Hydrogen Sulfide Detection From Earth to Space‐Like Environments
This work presents a gas sensing platform based on Cu‐doped SnO2 microspheres that operates reliably from ambient to space‐like conditions. The sensor maintains performance across vacuum and cryogenic environments, bypassing traditional oxygen‐mediated mechanisms, utilizing direct chemisorption and interfacial charge transfer.
Xi Chen +9 more
wiley +1 more source
Stochastic analysis and Monte Carlo simulation of magneto-opto-acoustic wave propagation in nonlocal semiconductor excitation. [PDF]
Elsakout DM, El-Dali A, Alaofi ZM.
europepmc +1 more source
Spatial‐Wavelength Multiplexing Error‐Controlled Photonic Analog Computing System
A novel photonic integrated circuit prototype implementing the concept of general‐purpose analog computing and demonstrate its capability in radio frequency applications. The chip features a multichannel architecture and performs fully optical analog computation with frequency‐domain parallel processing. An FPGA‐based error‐correction algorithm aims to
Tao Zhu +15 more
wiley +1 more source
Perpendicular ion heating in turbulence and reconnection: magnetic moment breaking by coherent fluctuations. [PDF]
Mallet A +4 more
europepmc +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Ocean transit times: from basin to planetary scales. [PDF]
Cessi P.
europepmc +1 more source
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño +5 more
wiley +1 more source
A Variational Formulation for Irreversible Thermodynamics with Path Dependence. [PDF]
Ren H.
europepmc +1 more source

