Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman +5 more
wiley +1 more source
Numerical Integration of Stochastic Differential Equations: The Heun Algorithm Revisited and the Itô-Stratonovich Calculus. [PDF]
Mannella R.
europepmc +1 more source
Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
Qualitative Analysis of a Nonautonomous Delayed Stochastic Predator-Prey Model with Beddington-DeAngelis Functional Response. [PDF]
Jia L, Wang C.
europepmc +1 more source
Bioenergy Cropping Reduces the Spatiotemporal Scaling of Soil Bacterial Biodiversity
Consistent with patterns observed in plant and animal communities, soil bacterial communities exhibit significant species–time–area and phylogenetic–time–area relationships independent of nested structure. Bioenergy cropping significantly reduces the spatiotemporal scaling rates, particularly in sandy loam soils.
Zhencheng Ye +19 more
wiley +1 more source
Numerical computation of the stochastic hepatitis B model using feed forward neural network and real data. [PDF]
Khan T, Jung IH.
europepmc +1 more source
Low‐frequency noise fingerprints in hafnia ferroelectrics provide a quantitative handle to resolve the long‐standing debate between polarization‐mediated and defect‐mediated switching. By tuning oxygen vacancy density via ALD O3 dose time and applying a physically constrained deconvolution, we extract bias‐resolved current fractions for both mechanisms
Ryun‐Han Koo +8 more
wiley +1 more source
Discrete stochastic maximal regularity. [PDF]
Evangelopoulos-Ntemiris F, Veraar M.
europepmc +1 more source
RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang +12 more
wiley +1 more source
Numerical modeling and simulation of stochastic fractional order model for COVID-19 infection in Mittag-Leffler kernel. [PDF]
Khan MA +4 more
europepmc +1 more source

