Results 51 to 60 of about 4,079 (268)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

The random Wigner distribution of Gaussian stochastic processes with covariance in S0(ℝ2d)

open access: yesJournal of Function Spaces and Applications, 2005
The paper treats time-frequency analysis of scalar-valued zero mean Gaussian stochastic processes on ℝd. We prove that if the covariance function belongs to the Feichtinger algebra S0(ℝ2d) then: (i) the Wigner distribution and the ambiguity function of ...
Patrik Wahlberg
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

On Fractional Hermite–Hadamard-Type Inequalities for Harmonically s-Convex Stochastic Processes

open access: yesFractal and Fractional
In this paper, we investigate Hermite–Hadamard-type inequalities for harmonically s-convex stochastic processes via Riemann–Liouville fractional integrals. We begin by introducing the notion of harmonically s-convex stochastic processes. Subsequently, we
Rabab Alzahrani   +3 more
doaj   +1 more source

An Averaging Principle for Stochastic Differential Delay Equations with Fractional Brownian Motion

open access: yesAbstract and Applied Analysis, 2014
An averaging principle for a class of stochastic differential delay equations (SDDEs) driven by fractional Brownian motion (fBm) with Hurst parameter in (1/2,1) is considered, where stochastic integration is convolved as the path integrals. The solutions
Yong Xu, Bin Pei, Yongge Li
doaj   +1 more source

Stochastic Electrodynamics: Lessons from Regularizing the Harmonic Oscillator

open access: yesAtoms, 2019
In this paper, the harmonic oscillator problem in Stochastic Electrodynamics is revisited. Using the exact shape of the Lorentz damping term prevents run-away effects.
Theodorus Maria Nieuwenhuizen
doaj   +1 more source

On Some Stochastic Integrals and a Stopped Brownian Motion [PDF]

open access: yesThe Egyptian Statistical Journal, 1979
For every non-negative number , let X(θ ,t) be a Brownian motion Let Tθ be the first time the process drops a specified amount below its maximum to data. We study stochastic integrals of the form Y(s) = ∫[0, s] v(θ) dw(θ) ,s ≥ 0, where W(θ) = x (θ,T) and
Khairia El-Nadi
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Non-Parametric Integral Estimation Using Data Clustering in Stochastic dynamic Programming: An Introduction Using Lifetime Financial Modelling

open access: yesRisks, 2017
This paper considers an alternative way of structuring stochastic variables in a dynamic programming framework where the model structure dictates that numerical methods of solution are necessary. Rather than estimating integrals within a Bellman equation
Gaurav Khemka, Adam Butt
doaj   +1 more source

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