Results 41 to 50 of about 3,282,695 (356)

Stochastic modeling of imperfect markets [PDF]

open access: yes, 2017
Stochastic optimization approaches ignore that the decisions of different actors in markets typically do not lead to a system-wide optimal solution.
Egging, Ruud, Baltensperger, Tobias
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Stochastic Modeling of Congress [PDF]

open access: yesThe Journal of Mathematical Sociology, 2012
We analyze the dynamics of growth of the number of congressmen supporting the resolution HR1207 to audit the Federal Reserve. The plot of the total number of co-sponsors as a function of time is of "Devil's staircase" type. The distribution of the numbers of new co-sponsors joining during a particular day (step height) follows a power law.
Simkin, M. V., Roychowdhury, V. P.
openaire   +2 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Gas Saturated Sandstone Reservoir Modeling Using Bayesian Stochastic Seismic Inversion

open access: yesJGEET: Journal of Geoscience, Engineering, Environment and Technology, 2020
This study has been done to map the distribution of gas saturated sandstone reservoir by using stochastic seismic inversion in the “X” field, Bonaparte basin. Bayesian stochastic inversion seismic method is an inversion method that utilizes the principle
Rahmat Catur Wibowo   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Nondeterminism in Stochastic Modeling [PDF]

open access: yes, 2003
This paper is devoted to the notion nondeterminism in general and particularly in stochastic modeling. It discusses how stochastic modeling formalisms can be mapped to a corresponding configuration graph which is convenient for the investigation of ...
Turetayev, Daulet
core   +1 more source

Advancing Cancer Research Through Stochastic Modeling: Insights into Tumor Growth, Evolution, and Treatment Response

open access: yesAppliedMath
The complex and heterogeneous nature of cancer necessitates advanced modeling techniques to better understand tumor dynamics and inform treatment strategies.
Tahmineh Azizi
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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