Results 41 to 50 of about 37,404 (267)

Transfer entropy and causal price spillovers between core and Southeast European electricity markets

open access: yesAcademia Green Energy
Introduction: This study examines the causal dynamics of electricity market integration and price differentials across seven European markets—Austria, Bulgaria, Greece, Hungary, Italy (South), Romania, and Slovenia—using the nonlinear ...
George P. Papaioannou   +2 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Development of an ice-jam flood forecasting modelling framework for freeze-up/winter breakup

open access: yesHydrology Research, 2023
River ice-jams can create severe flooding along many rivers in cold regions. While ice-jams often form during the spring breakup, the mid-winter breakup can cause ice-jamming and flooding.
Apurba Das   +2 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Analysis of Single-Cell Gene Pair Coexpression Landscapes by Stochastic Kinetic Modeling Reveals Gene-Pair Interactions in Development

open access: yesFrontiers in Genetics, 2020
Single-cell transcriptomics is advancing discovery of the molecular determinants of cell identity, while spurring development of novel data analysis methods.
Cameron P. Gallivan   +4 more
doaj   +1 more source

A unifying nonlinear probabilistic epidemic model in space and time

open access: yesScientific Reports, 2021
Covid-19 epidemic dramatically relaunched the importance of mathematical modelling in supporting governments decisions to slow down the disease propagation. On the other hand, it remains a challenging task for mathematical modelling.
Roberto Beneduci   +2 more
doaj   +1 more source

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

open access: yesFEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille   +6 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Optimal Design and Operation of Buffer Tanks Under Stochastic Conditions

open access: yesHungarian Journal of Industry and Chemistry, 2018
Safety regulations demand the elimination of random mistakes and the reliable operation of production units. However, the control and maintenance of batch and semi-continuous processes haalways been difficult.
Tarcsay Bálint Levente   +2 more
doaj   +1 more source

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