Results 31 to 40 of about 66,510 (262)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Diffusion Approximation and Optimal Stochastic Control [PDF]

open access: yesTheory of Probability & Its Applications, 2000
By the same goal with the previous paper of these authors [SIAM J. Control Optimization 34, No. 1, 161-178 (1996; Zbl 0867.93085)] but considering the case of a stochastic control model admitted a diffusion approximation, they show in the present paper that an optimal Lipschitz feedback control of the limit model \[ dX_t = [A_0 (t,X_t)+ a_1 (t,X_t)u_t]
Liptser, R.   +2 more
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

On the optimally controlled stochastic shallow lake

open access: yesInternational Journal of Control, 2023
We consider the stochastic control problem of the shallow lake and continue the work of G. T. Kossioris, Loulakis, and Souganidis (2019) in three directions. First, we generalise the characterisation of the value function as the viscosity solution of a well-posed problem to include more general recycling rates.
Angeliki Koutsimpela, Michail Loulakis
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Stochastic Control for Intra-Region Probability Maximization of Multi-Machine Power Systems Based on the Quasi-Generalized Hamiltonian Theory

open access: yesEnergies, 2019
With the penetration of renewable generation, electric vehicles and other random factors in power systems, the stochastic disturbances are increasing significantly, which are necessary to be handled for guarantying the security of systems.
Xue Lin, Lixia Sun, Ping Ju, Hongyu Li
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Optimal Control Algorithm for Stochastic Systems with Parameter Drift

open access: yesSensors, 2023
A novel optimal control problem is considered for multiple input multiple output (MIMO) stochastic systems with mixed parameter drift, external disturbance and observation noise.
Xiaoyan Zhang   +3 more
doaj   +1 more source

A Stochastic Gradient Descent Approach for Stochastic Optimal Control

open access: yesEast Asian Journal on Applied Mathematics, 2020
Summary: In this work, we introduce a stochastic gradient descent approach to solve the stochastic optimal control problem through stochastic maximum principle. The motivation that drives our method is the gradient of the cost functional in the stochastic optimal control problem is under expectation, and numerical calculation of such an expectation ...
Archibald, Richard   +2 more
openaire   +2 more sources

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