Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
Advanced Healthcare Materials, EarlyView.A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Exploiting Dual Connectivity for Handover Management in Heterogeneous Aeronautical Network
IEEE Access, 2019 In this paper, by introducing the software-defined networking (SDN) controller, we conduct traffic scheduling under dual connectivity (DC) pattern to support handover management in the heterogeneous aeronautical network.
Dongli Wang +5 more
doaj +1 more source
Scalable Orthonormal Projective NMF via Diversified Stochastic Optimization. [PDF]
Inf Process Med Imaging, 2023 Bani A +5 more
europepmc +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Stochastic Simulated Quantum Annealing for Fast Solution of Combinatorial Optimization Problems
IEEE AccessCombinatorial optimization problems are frequently classified as NP-hard, which means that the time needed to find the optimal solution generally increases exponentially with the problem size.
Naoya Onizawa +4 more
doaj +1 more source
Practicable robust stochastic optimization under divergence measures with an application to equitable humanitarian response planning. [PDF]
OR Spectr, 2023 Caunhye AM, Alem D.
europepmc +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
Advanced Materials, EarlyView.This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
Intelligent Acousto‐Electrical Metamaterials (IAM) for Sound Source Detection
Advanced Materials, EarlyView.Our proposed metamaterial concept enables sound source detection using a single material, in contrast to conventional arrays that require dozens or even hundreds of transducers. We show that the coupled acoustic–vibrational–electrical responses in piezoelectric metamaterials give rise to topology‐governed charge transport, producing distinct voltage ...
Victor Couëdel +7 more
wiley +1 more source
Stochastic optimization of a uranium oxide reaction mechanism using plasma flow reactor measurements. [PDF]
Sci Rep, 2023 Finko M +7 more
europepmc +1 more source
Advanced Materials, EarlyView.Ordered three‐dimensional anodic aluminum oxide (3D‐AAO) nanoarchitectures with longitudinal and transverse pores enable architecture‐driven metamaterials. The review maps fabrication advances, including hybrid pulse anodization, and shows how 3D‐AAO templates tailor properties across magnetism, energy, catalysis, and sensing.
Marisol Martín‐González
wiley +1 more source