Results 201 to 210 of about 555,552 (274)

Sulfate‐Directed Silver Dendrites with Enhanced Stability for Ultrasensitive SERS‐Based Therapeutic Drug Monitoring

open access: yesAdvanced Science, EarlyView.
This study presents sulfate‐directed silver dendrites (s‐AgDs) as oxidation‐resistant SERS substrates with long‐term stability, reproducibility, and sub‐picomolar sensitivity. Sulfate ions guide anisotropic growth and protect the surface, enabling improved performance over 7 months under ambient conditions.
Aradhana Dwivedi   +6 more
wiley   +1 more source

Perspective: Hollow Core Optical Fibres for Ultraviolet and Visible Wavelengths

open access: yesAdvanced Science, EarlyView.
Hollow core optical fibres bypass material constraints that limit optical fibres at ultraviolet and visible wavelengths. However, their challenging fabrication has limited their development, and significant gains in performance remain possible. In this perspective we outline approaches to enable the next generation of fibres for shorter wavelengths ...
Robbie Mears   +5 more
wiley   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

open access: yesAdvanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao   +8 more
wiley   +1 more source

MR‐DELTAnet: A Longitudinal MRI‐Transformer Model Predicting Pathological Complete Response and Revealing Immune Microenvironment via scRNA‐seq in Locally Advanced Rectal Cancer

open access: yesAdvanced Science, EarlyView.
The MR‐DELTAnet model utilizes longitudinal MRI to predict treatment response after neoadjuvant chemoradiotherapy in locally rectal cancer patients, accurately identifying patients likely to achieve pathological complete response for personalized management.
Wuteng Cao   +14 more
wiley   +1 more source

Real‐Time High‐Definition Hyperspectral Endoscopy via Spatial‐Temporal Low‐Frequency‐Stochastic Spectral Encoding

open access: yesAdvanced Science, EarlyView.
A real‐time, high‐definition hyperspectral endoscopy is enabled by developing a spatial‐temporal spectral encoding approach based on low‐frequency stochastic filters combined with an encoding‐guided attention network. It provides hyperspectral image of in vivo tissue with fine superficial features, enables visualization of rapid and subtle ...
Xiaowei Liu   +11 more
wiley   +1 more source

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

open access: yesAdvanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin   +6 more
wiley   +1 more source

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