Results 51 to 60 of about 168,286 (265)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

High-Order Disturbance Observer-Based Neural Adaptive Control for Space Unmanned Systems With Stochastic and High-Dynamic Uncertainties

IEEE Access, 2021
In this paper, a high order disturbance observer based stochastic adaptive anti-disturbance control algorithm has been designed for the space unmanned systems (SUSs) with high dynamic disturbances and stochastic uncertainties.
Yao Zhang, Xin Ning, Zheng Wang, Dengxiu Yu   +3 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Synchronization of Fractional Stochastic Chaotic Systems via Mittag-Leffler Function

Fractal and Fractional, 2022
This paper is involved with synchronization of fractional order stochastic systems in finite dimensional space, and we have tested its time response and stochastic chaotic behaviors.
T. Sathiyaraj, Michal Fečkan, JinRong Wang   +2 more
doaj   +1 more source

Transforming stochastic matrices for stochastic comparison with the st-order [PDF]

RAIRO - Operations Research, 2003
This paper deals with bounds on the steady state probability distributions of stochastic matrices, and gives a method of improving the bounds from their st-monotone upper bounding DTMC's.
Tugrul Dayar, Jean-Michel Fourneau, Nihal Pekergin   +2 more
openaire   +5 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Structural Properties of Optimal Maintenance Policies for k-out-of-n Systems with Interdependence Between Internal Deterioration and External Shocks

Mathematics
Many modern engineering systems, such as offshore wind turbines, rely on k-out-of-n configurations to ensure reliability. These systems are exposed to both internal deterioration and external shocks, which can significantly impact operational efficiency ...
Mizuki Kasuya, Lu Jin
doaj   +1 more source

Order and stochastic dynamics in Drosophila planar cell polarity. [PDF]

PLoS Computational Biology, 2009
Cells in the wing blade of Drosophila melanogaster exhibit an in-plane polarization causing distal orientation of hairs. Establishment of the Planar Cell Polarity (PCP) involves intercellular interactions as well as a global orienting signal. Many of the
Yoram Burak, Boris I Shraiman
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane, Salama Makni, Mourad Kchaou, Ahmed El Hajjaji   +3 more
wiley   +1 more source