Results 201 to 210 of about 237,776 (294)

Analytical insights and physical behavior of solitons in the fractional stochastic Allen-Cahn equations using a novel method. [PDF]

Sci Rep
Nazari-Golshan A.
europepmc   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

The critical helping hand of water: theory shows the way to obtain elusive, granular information about kinetic asymmetry driven systems. [PDF]

Chem Sci
Bajpai P, Thulasiram S, Vanka K.
europepmc   +1 more source

An Elastocaloric Polymer with Ultra‐High Solid‐State Cooling via Defect Engineering

Advanced Science, EarlyView.
This work reports a defect‐engineering strategy that enables a record‐high adiabatic temperature change of up to 8.14 ± 1.76 °C in elastomers at an elevated temperature above 65 °C. Combined experimental and theoretical efforts reveal that increasing dangling‐chain defects nonmonotonically impacts the elastocaloric cooling performance of polymers due ...
Zhaohan Yu, Duo Xu, Zumrat Usmanova, Chuwei Ye, Aditya Swarnkar, Emma Scott, Sizhe Huang, Siyuan Rao, Xinyue Liu, Svetlana V. Boriskina, Ruobing Bai, Shaoting Lin   +11 more
wiley   +1 more source

Structural integrity of RyR2 clusters controls cardiac calcium leak. [PDF]

Front Physiol
Noren A, Shiferaw Y.
europepmc   +1 more source

Modification Strategies of Carbon‐Based Electrodes From Structural Regulation to Multifunctional Integration

Advanced Science, EarlyView.
Tracing the evolution from structural regulation to multifunctional integration, this paper systematically analyzes modification strategies for carbon‐based electrodes. It evaluates how element doping, surface functionalization, and composite material design affect the electrode performance, and offers perspectives on future applications and challenges
Yunlei Wang, Shitao Dou, Yifan Wu, Mingguang Wang, Taibin Wu   +4 more
wiley   +1 more source

Numerical modeling and simulation of stochastic fractional order model for COVID-19 infection in Mittag-Leffler kernel. [PDF]

Sci Rep
Khan MA, Zafar ZUA, Ahmad I, Isa NM, Alzahrani E.   +4 more
europepmc   +1 more source

Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries

Advanced Science, EarlyView.
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang, Wenkai Wang, Zhenling Peng, Jianyi Yang   +3 more
wiley   +1 more source

Implementation and validation of the F⁴aT laboratory for flow in rough fractures. [PDF]

Sci Rep
Buness CM, Nitschke F, Kohl T.
europepmc   +1 more source