Three-dimensional stochastic simulation of chemoattractant-mediated excitability in cells. [PDF]
PLoS Comput Biol, 2021 Biswas D, Devreotes PN, Iglesias PA.
europepmc +1 more source
Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders
Advanced Science, EarlyView.BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley +1 more source
Exact Discrete Stochastic Simulation With Deep-Learning-Scale Gradient Optimization. [PDF]
Adv Sci (Weinh)Vilar JMG, Saiz L.
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Pharmacokinetic Model Based on Stochastic Simulation and Estimation for Therapeutic Drug Monitoring of Tacrolimus in Korean Adult Transplant Recipients. [PDF]
Ther Drug Monit, 2022 Choi S +5 more
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Inverse Design of Pre‐Strain via a Predictive Electromechanical Model for Enhanced Strain Sensing
Advanced Science, EarlyView.An analytical electromechanical model rooted in microcrack evolution mechanics is globally calibrated from only eight pre‐strain datasets, enabling prediction of the complete sensing response at untested pre‐strain values within the calibrated design space (R2 > 0.99).
Jia‐Chen Shang +10 more
wiley +1 more source
Simulation or cohort models? Continuous time simulation and discretized Markov models to estimate cost-effectiveness [PDF]
The choice of model design for decision analytic models in cost-effectiveness analysis has been the subject of discussion. The current work addresses this issue by noting that, when time is to be explicitly modelled, we need to represent phenomena ...
Marta O Soares, L Canto e Castro
core
LigninFit: Stochastic Simulation Software for the Prediction and Analysis of Experimentally Observed Lignin Molecules. [PDF]
Comput Struct Biotechnol JGahan L, Raguin A, De PS.
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Advanced Science, EarlyView.In this work, we demonstrated a robust 2D MoS2 based iontronic memtransistor of planar architecture operated under the influence of an electrical double layer with versatile performance and applications, including pinched hysteresis nature of transfer curve, analogue channel conductance tuning, low‐voltage operation, logic‐gate operation, classical ...
Puranjay Saha +2 more
wiley +1 more source
Using Stochastic Simulation-Estimation and Automated Model Development to Assess Power and Accuracy for Covariate Identification. [PDF]
CPT Pharmacometrics Syst PharmacolHsu YH +4 more
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A stochastic simulation model for assessing the masking effects of road noise for wildlife, outdoor recreation, and bioacoustic monitoring. [PDF]
Oecologia, 2022 Toth CA +6 more
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