Results 131 to 140 of about 365,256 (207)
Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance
Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos +5 more
wiley +1 more source
Linking the Comparison and Graphical Approaches to Bipartite Matching
Summary Bipartite record linkage has the goal of identifying observations referring to the same individual, called coreferent observations, across two distinct non‐duplicated datasets. The two main approaches to solve this task are the Fellegi–Sunter model, which relies on pairwise comparisons of observations, and the graphical record linkage model ...
Edoardo Redivo
wiley +1 more source
Financial Fragility and the Fiscal Multiplier
Abstract We show that undercapitalized banks with large holdings of government bonds subject to sovereign default risk lead to a new crowding‐out channel: deficit‐financed fiscal stimuli lead to higher bond yields, triggering capital losses for the banks. Banks then cut back loans, which reduces fiscal multipliers.
CHRISTIAAN VAN DER KWAAK +1 more
wiley +1 more source
African ape carpal morphology is not too specialized to represent the ancestral hominin carpus
Knuckle walking is one hypothesized behavior of the Pan‐Homo last common ancestor. We analyzed carpal morphology, including Euclidean distances between behavioral pairs, to investigate whether the carpals of knuckle‐walking taxa appear relatively specialized.
Laura E. Hunter +4 more
wiley +1 more source
Is the Gene‐ie Out of the Bottle? The Problems and Perils of Genetics Research in Management
Abstract In recent years, the field of management research has witnessed the emergence of a stream of research that seeks to identify the genetic determinants of managerial, entrepreneurial, and organizational behaviour. We challenge the reductionist epistemology underpinning this genetic perspective in management research and highlight the inherently ...
Jean Clarke +2 more
wiley +1 more source
Dynamic capital allocation in general insurance
Abstract This paper provides a model for allocating capital to different insurance lines with varying development periods for a value‐maximizing insurance company. In our model, the company makes capitalization and exposure decisions considering its capital level and its relevant loss history.
Qiheng Guo +2 more
wiley +1 more source
Beyond the Adult Mind: A Developmental Framework for Predictive Processing in Infancy
Abstract Predictive Processing has been proposed as the single unifying computation underlying all of cognition, and proponents argue that all psychological phenomena can be explained as consequences of this principle. This theoretical framework has inspired many cognitive scientists and neuroscientists, but it currently has no developmental mechanism ...
Emma K. Ward +4 more
wiley +1 more source
Nanosensor schematic functionalized with specific bioreceptors that produce electrochemical signals upon Chloramphenicol binding. Resulting voltammetric readouts (differential pulse, square‐wave, and cyclic voltammetry) are analyzed to identify and quantify Chloramphenicol.
Nava Moghadasian Niaki +5 more
wiley +1 more source
Abstract An agronomic trait such as stand count is important for cultivar development and crop management practices. Manually counting the number of plants is time consuming, labor‐intensive, and prone to error. The use of unoccupied aerial systems (UAS)‐collected red, green, blue (RGB) imagery in conjunction with advanced deep learning and image ...
Aliasghar Bazrafkan +1 more
wiley +1 more source
This study presents the computational components and workflow developed to conduct probabilistic seismic hazard analysis (PSHA) in New Zealand (NZ) using physics‐based ground‐motion simulations, referred to as “CyberShake NZ.” Semi‐automated procedures generate multiple realizations of kinematic rupture models, create rupture‐specific velocity models ...
Brendon A. Bradley +5 more
wiley +1 more source

