Results 131 to 140 of about 365,256 (207)

Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance

open access: yesImmunology, EarlyView.
Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos   +5 more
wiley   +1 more source

Linking the Comparison and Graphical Approaches to Bipartite Matching

open access: yesInternational Statistical Review, EarlyView.
Summary Bipartite record linkage has the goal of identifying observations referring to the same individual, called coreferent observations, across two distinct non‐duplicated datasets. The two main approaches to solve this task are the Fellegi–Sunter model, which relies on pairwise comparisons of observations, and the graphical record linkage model ...
Edoardo Redivo
wiley   +1 more source

Financial Fragility and the Fiscal Multiplier

open access: yesJournal of Money, Credit and Banking, EarlyView.
Abstract We show that undercapitalized banks with large holdings of government bonds subject to sovereign default risk lead to a new crowding‐out channel: deficit‐financed fiscal stimuli lead to higher bond yields, triggering capital losses for the banks. Banks then cut back loans, which reduces fiscal multipliers.
CHRISTIAAN VAN DER KWAAK   +1 more
wiley   +1 more source

African ape carpal morphology is not too specialized to represent the ancestral hominin carpus

open access: yesJournal of Anatomy, EarlyView.
Knuckle walking is one hypothesized behavior of the Pan‐Homo last common ancestor. We analyzed carpal morphology, including Euclidean distances between behavioral pairs, to investigate whether the carpals of knuckle‐walking taxa appear relatively specialized.
Laura E. Hunter   +4 more
wiley   +1 more source

Is the Gene‐ie Out of the Bottle? The Problems and Perils of Genetics Research in Management

open access: yesJournal of Management Studies, EarlyView.
Abstract In recent years, the field of management research has witnessed the emergence of a stream of research that seeks to identify the genetic determinants of managerial, entrepreneurial, and organizational behaviour. We challenge the reductionist epistemology underpinning this genetic perspective in management research and highlight the inherently ...
Jean Clarke   +2 more
wiley   +1 more source

Dynamic capital allocation in general insurance

open access: yesJournal of Risk and Insurance, EarlyView.
Abstract This paper provides a model for allocating capital to different insurance lines with varying development periods for a value‐maximizing insurance company. In our model, the company makes capitalization and exposure decisions considering its capital level and its relevant loss history.
Qiheng Guo   +2 more
wiley   +1 more source

Beyond the Adult Mind: A Developmental Framework for Predictive Processing in Infancy

open access: yesTopics in Cognitive Science, EarlyView.
Abstract Predictive Processing has been proposed as the single unifying computation underlying all of cognition, and proponents argue that all psychological phenomena can be explained as consequences of this principle. This theoretical framework has inspired many cognitive scientists and neuroscientists, but it currently has no developmental mechanism ...
Emma K. Ward   +4 more
wiley   +1 more source

Clinical Laboratory Innovations: Nanoscale Detection of Chloramphenicol Using Nanomaterial Biosensors

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
Nanosensor schematic functionalized with specific bioreceptors that produce electrochemical signals upon Chloramphenicol binding. Resulting voltammetric readouts (differential pulse, square‐wave, and cyclic voltammetry) are analyzed to identify and quantify Chloramphenicol.
Nava Moghadasian Niaki   +5 more
wiley   +1 more source

Pixel‐level supervision resolves overlap: Benchmarking YOLOv12 segmentation for accurate multi‐cluster dry bean stand counting from time series unoccupied aerial systems imagery

open access: yesThe Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract An agronomic trait such as stand count is important for cultivar development and crop management practices. Manually counting the number of plants is time consuming, labor‐intensive, and prone to error. The use of unoccupied aerial systems (UAS)‐collected red, green, blue (RGB) imagery in conjunction with advanced deep learning and image ...
Aliasghar Bazrafkan   +1 more
wiley   +1 more source

CyberShake NZ: Probabilistic Seismic Hazard Analysis in New Zealand Using Physics‐Based Ground‐Motion Simulations

open access: yesEarthquake Spectra, Volume 42, Issue 4, November 2026.
This study presents the computational components and workflow developed to conduct probabilistic seismic hazard analysis (PSHA) in New Zealand (NZ) using physics‐based ground‐motion simulations, referred to as “CyberShake NZ.” Semi‐automated procedures generate multiple realizations of kinematic rupture models, create rupture‐specific velocity models ...
Brendon A. Bradley   +5 more
wiley   +1 more source

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