Results 91 to 100 of about 1,273,882 (314)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

The ADP/FS frame survey of Lake Kyoga and Lake Kwania [PDF]

open access: yes, 1990
The report provides a summary of the frame survey results carried out in lakes Kyoga and Kwania in 1990. The ADP Fisheries Survey of Lake Kyoga is charged with a stock-assessment programme.
Hartsuijker, L., Kibwika, D., Twongo, T.
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Stock assessment and management recommendations for Pacific sardine (Sardinops sagax) in 1997 [PDF]

open access: yes, 1998
The primary goal of sardine management as directed by the California Fish and Game Code is rehabilitation of the resource with an added objective of maximizing sustained harvest.
Hanan, Doyle A.   +4 more
core  

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

Evaluation of a spatiotemporal index standardization method for coastal shark species; implications for future stock assessments

open access: yesFrontiers in Marine Science
IntroductionMethods combining data from spatially limited, independently conducted surveys indicate a preliminary recovery for coastal shark species along the Atlantic.
Kaitlyn A. O’Brien   +5 more
doaj   +1 more source

On financial derivatives and differential equations used in their assessment [PDF]

open access: yes
This paper deals with the assessment of options on dividend paying stock and futures options. We start from the case of the underlying asset who does not generate dividend and then switch to an underlying asset which pays a continuous dividend yield. The
Albici, Mihaela, Teselios, Delia
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Importance of near-bottom oceanographic data in modeling the distribution of eulachon bycatch in the U.S. West Coast shrimp trawl fishery

open access: yesFrontiers in Marine Science
IntroductionSpecies distribution models (SDMs) are increasingly used in fisheries science to understand species’ spatial patterns and improve stock assessments.
Leif K. Rasmuson   +6 more
doaj   +1 more source

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