Results 61 to 70 of about 34,455 (262)

First data on the age and growth of Brazilian flathead Percophis brasiliensis (Pisces: Perciformes) in San Matías Gulf, northern Patagonia (Argentina)

Marine and Fishery Sciences, 2020
Brazilian flathead Percophis brasiliensis is a commercially important perciform fish caught as bycatch by trawlers throughout its latitudinal distribution range (from 23° S in Brazil to 47° S in Argentina).
María E. López, Matías Ocampo Reinaldo, Karina A. Rodrígues, M. Rita Rico, Margarita E. Sáez, Raúl A. González   +5 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

Advanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali, Zeeshan Alam Ansari, Reynaldo Carlos Kuizon Montalbo, Hailemichael Ayalew, Yu‐Sheng Hsiao, Chih‐Wei Chu, Hsiao‐hua Yu, Hsiung‐Lin Tu   +7 more
wiley   +1 more source

Shape Analysis of Otoliths of the Round goby, Neogobius melanostomus (Gobiiformes, Gobiidae), from the Black Sea Basin

Zoodiversity, 2021
This study aims to assess the round goby Neogobius melanostomus stocks discriminability based on the shape of its otoliths. Recent otolith-shape-based species and stock discrimination studies have been using otoliths’ contours in sagittal plane and we ...
V. Zamorov, M. Zamorova, D. Krupko, N. Matvienko, Y. Leonchyk, Y. Kvach   +5 more
doaj  

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Determinants of Board Diversity for Firms Listed on the Zimbabwe Stock Exchange [PDF]

International Journal of Business and Development Studies
Board diversity is a topical discourse in firm governance and management. Diversity came up as a way of eliminating discrimination in employment and making sure there is equality, inclusion and affirmative action in the way firms do business.
Zvinaiye Chimbadzwa, Lighton Dube, Emmanuel Guveya   +2 more
doaj   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

Stock discrimination of Rutilus rutilus by using Otoliths

, 2004
Iranian Fisheries Science Research ...
Parafkandeh Haghighi, Farokh, Rezvani, S., Taghavi, A., Peyrovan, H., Pourang, N., Boorani, M.S., Moghim, M.   +6 more
openaire   +1 more source

Morphometric discrimination of pelagic fish stocks challenged by variation in body condition

ICES Journal of Marine Science, 2017
Abstract Morphometric characters have traditionally been used to describe the population structure of fishes. Body shape variation, which is often environmentally induced, may provide a good record of short-term population structuring.
George Geladakis, Nikolaos Nikolioudakis, George Koumoundouros, Stylianos Somarakis   +3 more
openaire   +1 more source