A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji +8 more
wiley +1 more source
Establishing a common metric for patient-reported outcomes in cancer patients: linking patient reported outcomes measurement information system (PROMIS), numerical rating scale, and patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE). [PDF]
Lee MK +6 more
europepmc +1 more source
The current utilization of the patient-reported outcome measurement information system (PROMIS) in isolated or combined total knee arthroplasty populations. [PDF]
Gupta P +5 more
europepmc +1 more source
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi +7 more
wiley +1 more source
Creating a developmental scale to chart the development of psychopathology with different informants and measures across time. [PDF]
Petersen IT, LeBeau B.
europepmc +1 more source
Bhāskara I's versified solutions of a linear indeterminate equation [PDF]
International audienceAt the end of Bhāskara's 7th century commentary on the mathematical part of the Āryabhaṭīya 91 verses provide solutions of linear indeterminate equations using astral parameters.
Keller, Agathe
core +2 more sources
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues +6 more
wiley +1 more source
Linking of Rasch-Scaled Tests: Consequences of Limited Item Pools and Model Misfit. [PDF]
Fischer L +3 more
europepmc +1 more source
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai +6 more
wiley +1 more source
Item Response Thresholds Models: A General Class of Models for Varying Types of Items. [PDF]
Tutz G.
europepmc +1 more source

