Results 21 to 30 of about 7,321 (222)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Penyetaraan Tes Berbentuk Uraian [PDF]
, 2006 Skor dari dua paket tes yang mengukur kemampuan yang sama yang dibuat dengan kisi‐kisi yang sama tidak dapat diperbandingkan langsung, karena skor tes tersebut belum berada pada skala yang sama. Skor tes yang dapat dibandingkan
Kartono, Kartono
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Beyond Savagery: The Limits of Australian ‘Aboriginalism’ [PDF]
, 2011 Ideas and representations of the supposedly savage condition of the New World's indigenous peoples have informed a now familiar account of colonialism. These have been understood as the ‘constructions’ of a discourse concerned to justify its ...
Anderson, Kay, Perrin, Colin
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
MYTH AND REALITY:ORGANIC VS NON-ORGANIC [PDF]
, 2001 This report examines some of the key issues around organic food and its production. It takes up the challenge of answering the critics - critics who range from companies defending agri-business, through to the heads of national food authorities and some ...
Azeez, Ms G
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Modelling the Marginal Abatement Cost of Mitigating Nitrogen Loss from Agricultural Land [PDF]
, 2012 working paperWith the deadline identified by the Water Framework Directive (2000/60/EC) approaching in 2015 there is increasing pressure on policymakers to introduce new regulations to achieve water quality targets.
Buckley, Cathal +5 more
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Race, populations, and genomics: Africa as laboratory [PDF]
, 2008 http://dx.doi.org/10.1016/j.socscimed.2008.07 ...
Braun, Lundy, Hammonds, Evelynn
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source