Results 231 to 240 of about 5,199,297 (296)

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Effects of Different Stocking Densities on Growth Performance, Stress Resistance, Antioxidant Capacity and Immunity of Grass Carp. [PDF]

Animals (Basel)
Wu Z, Xu Q, Feng L, Wang J, Xu Y, Wu Y, Zhou L, Xu J.   +7 more
europepmc   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

Potential role of dietary red onion peel polyphenol-rich extract in enhancing growth, feed utilization, and antioxidant and immune responses in Nile tilapia (Oreochromis niloticus) cultured at high stocking density. [PDF]

Fish Physiol Biochem
Al-Sagheer AA, Ayyat AMN, Ahmed NH, Ayyat MS, Osman A, El-Latif KMA.   +5 more
europepmc   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Regenerative agriculture improves productivity and profitability while reducing greenhouse gas emissions on Australian sheep farms. [PDF]

Nat Food
Muleke A, Christie-Whitehead KM, Cain M, Liu K, Burgess PJ, Wiltshire C, Pexas G, Harrison MT.   +7 more
europepmc   +1 more source

High Levels of Straying in Returning, Repeat-Spawning Atlantic Salmon Between Two Neighbouring Danish Rivers. [PDF]

Ecol Evol
Flávio H, Klubben Sortland L, Birnie-Gauvin K, Koed A, Larsen S, Aarestrup K.   +5 more
europepmc   +1 more source