Results 51 to 60 of about 20,020 (261)

Sheep wool δ13C reveals no effect of grazing on the C3/C4 ratio of vegetation in the inner Mongolia-Mongolia border region grasslands. [PDF]

open access: yesPLoS ONE, 2012
We tested whether the abundance of C(4) vegetation in grasslands of the Mongolian plateau is influenced by grazing conditions. The analysis exploited the politically originated contrast that exists between Mongolia (low stocking rate, transhumant system)
Karl Auerswald   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

THE IMPACT OF DIFFERENT STOCKING DENESITIES AND DIETARY PROTEIN LEVELS ON THE PERFORMANCE OF AFRICAN CATFISH (Clarias gariepinus) FINGERLINGS

open access: yesSlovenian Veterinary Research, 2019
The current experiment was randomly  designed  as  a 3×2 factorial design to investigate the effects of two fixed factor (stocking density & dietary protein level) on growth performance, feed utilization, survival rate and physiological response of ...
Fawzy Magouz   +3 more
doaj   +1 more source

An evaluation of the DDH/100 mm stocking rate index and an alternative approach to stocking rate estimation [PDF]

open access: yesThe Rangeland Journal, 2007
Long-term data for (simulated) daily pasture growth and moving 12-monthly rainfall totals were used to examine the performance of the DDH/100 mm stocking rate index under theoretically ideal management for three locations in the Western Division of NSW.
R. B. Hacker, W. J. Smith
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Cattle production supplemented on signal grass pastures during the rainy season

open access: yesActa Scientiarum: Animal Sciences, 2016
The effects of four supplement doses (0, 1, 2 and 3 kg animal-1 day-1) on pasture characteristics and on cattle production on Brachiaria decumbens cv. Basilisk pastures in continuous stocking with variable stocking rate were assessed. Experimental design
Manoel Eduardo Rozalino Santos   +5 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

DETERMINATION OF THE BEST STOCKING DENSITY FOR REARING HUSO HUSO

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2007
Effects of stocking density on growth, food conversion ratio, specific growth rate, percentage of body weight increase in Huso huso were studied in two phases. Juveniles below one year old with an average weight of 92.09±1.72 grams and stocking densities
M. Mohseni; H. Porali; M. Sajadi; V. Aghtoman
doaj  

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