Results 51 to 60 of about 431,587 (304)

Influence of random fluctuations on delayed bifurcations. II. The cases of white and colored additive and multiplicative noise [PDF]

open access: yes, 1990
The influence of noise on the delay of a bifurcation point in the presence of a swept control parameter has been investigated theoretically, by digital simulation and by analog electronic experiment. The results obtained in an earlier paper [N. G. Stocks,
MCCLINTOCK PVE   +5 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

DNA markers help manage Nile tilapia stocks

open access: yes, 2006
Determining changes in the genetic diversity of selected hatchery stocks through DNA-level polymorphisms analysis provides aquaculturists with a means to monitor inbreeding, control loss of genetic diversity, and achieve sustainable levels of genetic ...
Taniguchi, Nobuhiko   +1 more
core   +2 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Monsters in the Night: Hannibal, Prodigia, and the Parallel Worlds of Epode 16 and Ode 4.4

open access: yes, 2016
Item does not contain ...
Stocks, C.A., Claire Stocks
core   +1 more source

THE IMPORTANCE AND ROLE OF INTERNAL AUDIT MISSIONS OF STOCKS [PDF]

open access: yesAnnals of the University of Craiova: Economic Sciences Series, 2020
In the case of entities with a significant inventory/stocks turnover, the implementation of internal audit function must be a concern of both management and shareholders, in order to prevent and detect the risk of embezzlement of these assets.
Maria-Andreia Iliescu (Ristea)   +3 more
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Why Are Stocks So Risky? [PDF]

open access: yes
With the decline in privately and publicly guaranteed benefits for pensions and health care, people increasingly must finance a greater share of their retirement expenses through their own savings.
Richard W. Kopcke, Dan Muldoon
core  

Home - About - Disclaimer - Privacy