Results 51 to 60 of about 216,785 (214)
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Ribogospodarsʹka Nauka UkraïniPurpose. To analyze and summarize the biological parameters of the main commercial species of aquatic bioresources using the example of bream, common carp, roach, Prussian carp and pikeperch of the Zaporizhzhia (Dnipro) Reservoir under conditions of ...
O. Marenkov +4 more
doaj +1 more source
Testing the Logistics Model of Supplying Military Vehicles with Spare Parts
Promet (Zagreb), 2007 The use of advanced transport means understands alsotheir supply by spare and consumable parts. In order to solvethe problem of the required quantities, costs of purchase andstorage of the parts, it is necessary to solve the problem of stocksmanagement ...
Robert Spudić +2 more
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FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Elements Regarding the Presence of Foreign Direct Investments in Romania – Case Study [PDF]
Ovidius University Annals: Economic Sciences Series, 2020 The study, briefly, presents aspects of the penetration of foreign capital in the Romanian economy, after 1990, and the impact on its development. The case study analyses the trends recorded in the evolution of the flow of Foreign Direct Investments, in ...
Florina Popa
doaj
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Экономика: стратегия и практикаThis study delves into the optimization of investment portfolios within the Unified Accumulative Pension Fund in Kazakhstan, employing the Quasi-Sharp model as a pivotal tool.
A. U. Amirova +3 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source