Results 51 to 60 of about 431,587 (304)
Influence of random fluctuations on delayed bifurcations. II. The cases of white and colored additive and multiplicative noise [PDF]
The influence of noise on the delay of a bifurcation point in the presence of a swept control parameter has been investigated theoretically, by digital simulation and by analog electronic experiment. The results obtained in an earlier paper [N. G. Stocks,
MCCLINTOCK PVE +5 more
core +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
DNA markers help manage Nile tilapia stocks
Determining changes in the genetic diversity of selected hatchery stocks through DNA-level polymorphisms analysis provides aquaculturists with a means to monitor inbreeding, control loss of genetic diversity, and achieve sustainable levels of genetic ...
Taniguchi, Nobuhiko +1 more
core +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Monsters in the Night: Hannibal, Prodigia, and the Parallel Worlds of Epode 16 and Ode 4.4
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Stocks, C.A., Claire Stocks
core +1 more source
THE IMPORTANCE AND ROLE OF INTERNAL AUDIT MISSIONS OF STOCKS [PDF]
In the case of entities with a significant inventory/stocks turnover, the implementation of internal audit function must be a concern of both management and shareholders, in order to prevent and detect the risk of embezzlement of these assets.
Maria-Andreia Iliescu (Ristea) +3 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Why Are Stocks So Risky? [PDF]
With the decline in privately and publicly guaranteed benefits for pensions and health care, people increasingly must finance a greater share of their retirement expenses through their own savings.
Richard W. Kopcke, Dan Muldoon
core

