Results 51 to 60 of about 177,861 (299)

Stoichiometry dependence of hardness, elastic properties, and oxidation resistance in TiN/SiNx nanocomposites deposited by a hybrid process [PDF]

open access: yes, 2004
TiN/SiNx nanocomposite layers with Si contents between 0 and 25 at. % were deposited by a reactive arc-magnetron sputtering hybrid process. The stoichiometry of the SiNx phase was found to be related to the silicon sputter target state, i.e., elemental ...
F.-J. Haug   +11 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Drivers of Cyanobacterial Blooms in a Hypertrophic Lagoon

open access: yesFrontiers in Marine Science, 2018
The Curonian Lagoon is Europe’s largest lagoon and one of the most seriously impacted by harmful blooms of cyanobacteria. Intensive studies over the past 20 years have allowed us to identify the major drivers determining the composition and spatial ...
Marco Bartoli   +19 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Single Viruses on the Fluorescence Microscope: Imaging Molecular Mobility, Interactions and Structure Sheds New Light on Viral Replication

open access: yesViruses, 2018
Viruses are simple agents exhibiting complex reproductive mechanisms. Decades of research have provided crucial basic insights, antiviral medication and moderately successful gene therapy trials. The most infectious viral particle is, however, not always
Nagma Parveen   +3 more
doaj   +1 more source

Intraspecific Trait Variability of a Diatom and a Dinoflagellate Along a Salinity Gradient

open access: yesFrontiers in Marine Science, 2022
The phytoplankton community is a highly diverse group of microscopic, photosynthetic organisms responsible for 50% of the global primary production.
Iris Delos Santos Orizar   +1 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Role of Lakes, Flood, and Low Flow Events in Modifying Catchment‐Scale DOC:TN:TP Stoichiometry and Export

open access: yesWater Resources Research
The balance of organic carbon (OC), nitrogen (N) and phosphorus (P) plays a crucial role in determining the processing, retention, and movement of these solutes across the aquatic continuum.
Christina Fasching   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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