Results 191 to 200 of about 42,500 (264)

Hippocampal network activity changes during early epileptogenesis predict subsequent epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Despite decades of research, the circuit mechanisms that underlie focal epileptogenesis remain incompletely understood. In this study, we aimed to characterize the changes in hippocampal network activity induced by an epileptogenic insult.
Michael Strüber   +13 more
wiley   +1 more source

Status epilepticus in adults: From etiology to treatment response

open access: yesEpilepsia, EarlyView.
Abstract This study explored the association between etiology of status epilepticus (SE) and treatment responsiveness. Consecutive episodes of nonhypoxic SE in patients ≥14 years old were included. Etiology was classified into acute, remote, progressive, defined electroclinical syndromes, and unknown.
Simona Lattanzi   +5 more
wiley   +1 more source

How should etiology change the classification of the epilepsies? Report from the ILAE 2021–2025 Terminology Commission

open access: yesEpilepsia, EarlyView.
Abstract The classification of the epilepsies has traditionally relied on clinical and electroencephalographic features. However, advancements in molecular genetics, neuroimaging, and our understanding of epilepsy pathophysiology necessitate a shift toward an etiology‐based approach.
Nicola Specchio   +15 more
wiley   +1 more source

Turing complete Navier-Stokes steady states via cosymplectic geometry. [PDF]

open access: yesPNAS Nexus
Dyhr S   +3 more
europepmc   +1 more source

Non‐contrast MRI reliably captures perfusion abnormalities in status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective To determine whether non‐contrast pseudo‐continuous arterial spin labeling (pCASL) detects status epilepticus (SE)–related perfusion abnormalities and shows quantitative correspondence with dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI), and to compare single‐slice and volumetric approaches for ...
Lukas Machegger   +5 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

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