Hippocampal network activity changes during early epileptogenesis predict subsequent epilepsy
Abstract Objective Despite decades of research, the circuit mechanisms that underlie focal epileptogenesis remain incompletely understood. In this study, we aimed to characterize the changes in hippocampal network activity induced by an epileptogenic insult.
Michael Strüber +13 more
wiley +1 more source
Experimental and CFD investigation of the dynamic characteristics of particle clusters under cavitation bubble near a rigid wall. [PDF]
Shen X, Han W, Li R, Yang S, Meng Q.
europepmc +1 more source
Status epilepticus in adults: From etiology to treatment response
Abstract This study explored the association between etiology of status epilepticus (SE) and treatment responsiveness. Consecutive episodes of nonhypoxic SE in patients ≥14 years old were included. Etiology was classified into acute, remote, progressive, defined electroclinical syndromes, and unknown.
Simona Lattanzi +5 more
wiley +1 more source
Bridging strategies for heart-lung transplantation: Current concepts and mechanical support modalities. [PDF]
Hoetzenecker K +3 more
europepmc +1 more source
Abstract The classification of the epilepsies has traditionally relied on clinical and electroencephalographic features. However, advancements in molecular genetics, neuroimaging, and our understanding of epilepsy pathophysiology necessitate a shift toward an etiology‐based approach.
Nicola Specchio +15 more
wiley +1 more source
Turing complete Navier-Stokes steady states via cosymplectic geometry. [PDF]
Dyhr S +3 more
europepmc +1 more source
Non‐contrast MRI reliably captures perfusion abnormalities in status epilepticus
Abstract Objective To determine whether non‐contrast pseudo‐continuous arterial spin labeling (pCASL) detects status epilepticus (SE)–related perfusion abnormalities and shows quantitative correspondence with dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI), and to compare single‐slice and volumetric approaches for ...
Lukas Machegger +5 more
wiley +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Graphene oxide nanoparticles oscillation in drilling fluid for heat transfer with entropy generation over radiative cylinder in fluctuating and laminar regimes. [PDF]
Khedher NB +8 more
europepmc +1 more source

