Results 141 to 150 of about 90,108 (307)
Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors
Advanced Science, EarlyView.This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng +12 more
wiley +1 more source
Applications in Engineering ScienceThe stability of steady, fully developed flow in a long cylindrical pipe for a shear-thinning fluid (which approximates a class of viscoplastic materials) is studied using linear stability analysis. The eigenvalues of the frequency of the perturbation of
Mohan Anand +2 more
doaj +1 more source
A primer on direct numerical simulation of turbulence - methods, procedures and guidelines
, 2010 Direct Numerical Simulation (DNS) is the branch of CFD devoted to high-fidelity solution ofturbulent flows. DNS differs from conventional CFD in that the turbulence is explicitly resolved,rather than modelled by a Reynolds-averaged Navier-Stokes (RANS ...
Sandberg, Richard D., Coleman, Gary N.
core
Advanced Science, EarlyView.By engineering the molecular order and thickness of PDMS layers, we reconcile the stickiness and slipperiness during bubble transport. AFM measurements and MD simulations further reveal how these nanoscale architectures tune hydrophobic interaction FHB and friction force f.
Shishuang Zhang +7 more
wiley +1 more source
Large eddy simulation of buoyant plumes [PDF]
, 2003 A 3d parallel CFD code is written to investigate the characteristics of and differences between Large Eddy Simulation (LES) models in the context of simulating a thermal buoyant plume. An efficient multigrid scheme is incorporated to solve the Poisson
Worthy, Jude
core
Advanced Science, EarlyView.Integrating experimental insights with molecular dynamics simulations, we establish an advanced mathematical model for fluids confined in sub‐10‐nm channels, enabling quantitative prediction of interfacial layer thickness and viscosity by accounting for channel material, temperature, and fluid properties.
Xiang Zhang +3 more
wiley +1 more source
Penyusunan Model Elemen Hingga Interaksi Persamaan Aliran dengan Persamaan Sebaran Udara
Semesta Teknika, 2015 Aeration process is one of water treatment processes. The process consists of two physical phenomena, flow, and spreading of air bubble. This research has developed a finite element model for three-dimensional flow and spreading of air bubble.
Jazaul Ikhsan , Adam Pamudji Rahardjo
doaj
Exponential asymptotics with multiple stokes lines
, 2009 When asymptotic series methods are applied in order to solve problems that arise in applied mathematics in the limit that some parameter becomes small, they are unable to demonstrate behaviour that occurs on a scale that is exponentially small compared ...
Lustri, Christopher Jessy
core
LES and RANS for turbulent flow over arrays of wall-mounted obstacles
, 2006 Large-eddy simulation (LES) has been applied to calculate the turbulent flow over staggered wall-mounted cubes and staggered random arrays of obstacles with area density 25%, at Reynolds numbers between 5 × 10^3 and 5 10^6, based on the free stream ...
Zhengtong Xie +3 more
core +1 more source
Observation of Excitonic Instability in a Monolayer Ta2NiSe5 With Strain Disorder
Advanced Science, EarlyView.Monolayer Ta2${\rm Ta}_2$NiSe5${\rm NiSe}_5$ sustains an excitonic insulating phase up to 190 K, with Raman signatures of gap opening and critical excitonic fluctuations. Thickness‐independent large gap ratios highlight strong exciton‐phonon coupling, while substrate‐induced strain disorder depresses Tc, establishing monolayer Ta2${\rm Ta}_2$NiSe5${\rm
So Young Kim +13 more
wiley +1 more source