Results 101 to 110 of about 5,062,400 (385)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Gastric Cancer at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 232 Cases. [PDF]

open access: yes, 2012
Despite marked decreases in its incidence, particularly in developed countries, gastric cancer is still the second most common tumor worldwide. There is a paucity of information regarding gastric cancer in northwestern Tanzania. This study was undertaken
Chalya, Phillipo L   +7 more
core   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

The overall structure of microbiota in patients with adenocarcinoma stomach and colon cancer

open access: yesJournal of Education, Health and Sport, 2020
IntroductionAccumulating evidence suggests that the human bowel microbiota contributes to the etiology of colorectal cancer (CRC) and stomach cancer, not only via the pro-carcinogenic activities of specific pathogens but also via the influence of the ...
O. V. Movchan
doaj   +1 more source

Risk factors in gastric cancer [PDF]

open access: yes, 2010
STATE OF THE ART: Gastric cancer (GC) is still a major health problem worldwide due to its frequency, poor prognosis and limited treatment options. At present prevention is likely to be the most effective means of reducing the incidence and mortality ...
COMPARE, DEBORA   +2 more
core  

Constructing Ontology-Based Cancer Treatment Decision Support System with Case-Based Reasoning [PDF]

open access: yes, 2018
Decision support is a probabilistic and quantitative method designed for modeling problems in situations with ambiguity. Computer technology can be employed to provide clinical decision support and treatment recommendations.
Colloc, Joël   +4 more
core   +1 more source

Using RNN Artificial Neural Network to Predict the Occurrence of Gastric Cancer in the Future of the World

open access: yesInternational Journal of Innovative Science and Research Technology
Gastric cancer is an important health problem and is the fourth most common cancer and the second leading cause of cancer-related deaths worldwide. The incidence of stomach cancer is increasing and it can be dealt with using new methods in prediction and
Seyed Masoud Ghoreishi Mokri   +2 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

The XRCC 1 DNA repair gene modifies the environmental risk of stomach cancer: a hospital-based matched case-control study

open access: yesBMC Cancer, 2017
Background Previous studies have found that polymorphisms of the DNA repair gene X-ray repair cross-complementing group 1(XRCC1) and environmental factors are both associated with an increased risk of stomach cancer, but no study has reported on the ...
Nuntiput Putthanachote   +8 more
doaj   +1 more source

Plasticity of differentiated cells in wound repair and tumorigenesis, Part II: Skin and intestine [PDF]

open access: yes, 2018
Recent studies have identified and begun to characterize the roles of regenerative cellular plasticity in many organs. In Part I of our two-part Review, we discussed how cells reprogram following injury to the stomach and pancreas.
Burclaff, Joseph, Mills, Jason C
core   +2 more sources

Home - About - Disclaimer - Privacy