Results 81 to 90 of about 257,686 (307)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Case-Control Study of Dietary Pattern and Other Risk Factors for Gastric Cancer [PDF]

The rates of gastric cancer reported from Ardabil Province of Iran, are among the highest in the world. The aim of this study was to investigate the risk factors for gastric cancer in Ardabil Province.
نعمتی, علی, مهدوی, رضا, نقی زاده باقی, عباس   +2 more
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Cancer incidence and mortality in Portugal.

, 2003
In this paper, we present estimates of national cancer incidence in Portugal in 1996-1998, predictions for the year 2000, and interpret the recent cancer mortality trends in light of observations from epidemiological research and risk factor patterns. In
Pinheiro, PS, Tyczyński, JE, Pinheiro, P.S, Matos, E, Bray, F, Amado, J, Tyczyński, J.E, Parkin, D.M, Parkin, DM   +8 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation [PDF]

, 2007
<b>Background</b>: The major potential site of acid nitrosation is the proximal stomach, an anatomical site prone to a rising incidence of metaplasia and adenocarcinoma.
Paterson, S., Crozier, A., Winter, J., Iijima, K., Preston, T., Combet, E., Mullen, W., McColl, K.E.L.   +7 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Gastric Cancer in Ardabil, Iran - a Review and Update on Cancer Registry Data [PDF]

The incidence rate of gastric cancer in western countries has shown a remarkable decline in recent years while it is still the most common cancer among men in Iran. Ardabil, a North Western province, was found to have the highest rate of GC in Iran and
درخشان, محمدحسین, موسوی, سید محسن, بابایی, مسعود, رحیمی, گیتی, پورفرضی, فرهاد, صمدی, فاطمه, چینی فروش, میرمهدی, یزدانبد, عباس   +7 more
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HIV infection and domestic smoke exposure, but not human papillomavirus, are risk factors for esophageal squamous cell carcinoma in Zambia: a case-control study

, 2015
(c) 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original ...
Asombang, AW, Kanekwa Zyambo, Aaron Shibemba, Shibemba, Aaron, Asombang, Akwi W., Zyambo, K, Themba Banda, Allen C. Bateman, Banda, Themba, Rose Soko, Soko, Rose, Paul Kelly, Bateman, AC, Kayamba, Violet, Soko, R, Zyambo, Kanekwa, Banda, T, Kayamba, V, Bateman, Allen C., Kelly, Paul, Violet Kayamba, Akwi W. Asombang, Shibemba, A, Kelly, P   +23 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Survival rate of gastric and esophageal cancers in Ardabil Province, North-West of Iran [PDF]

Background: Upper gastrointestinal cancer is the most common cancer in Ardabil Province, North-West of Iran, accounting for more than 50% of all cancer deaths in this area.
درخشان, محمدحسین, ملک زاده, رضا, نصراله زاده, داریوش, بابایی, مسعود, سجادی, علیرضا, شکوهی گوگانی, بهروز, صمدی, فاطمه, فلاح, مهدی, یزدانبد, عباس, فولادی, رباب, نورایی, مهدی   +10 more
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