Results 61 to 70 of about 4,846,336 (342)

Incidence and mortality of stomach cancer in Shandong Province in 2012

Precision Radiation Oncology, 2018
Stomach cancer is common in the Chinese population. The present study aimed to analyze the incidence and mortality as a result of stomach cancer in Shandong Province, in order to provide a reference for cancer prevention and control.
Zhentao Fu, Guigang Li, Jandong Sun, Yuting Zhai, Jiyu Zhang, Zilong Lu, Jie Chu, Gaohui Zhang, Xiaolei Guo, Aiqiang Xu   +9 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Epidemiology characteristics and trends of incidence and morphology of stomach cancer in Iran.

Asian Pacific Journal of Cancer Prevention, 2015
BACKGROUND Stomach cancer is the fourth most common cancer and the second leading cause of cancer- related death through the world. It is predicted that the number of new cancer cases will be more than 15 million cases by 2020.
Zeinab Almasi, H. Rafiemanesh, H. Salehiniya   +2 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

SIMULTANEOUS SURGICAL TREATMENT OF STOMACH CANCER AND JEJUNAL DIVERTICULOSIS

Паёми Сино, 2021
The article presents a case of a combination of stomach cancer and jejunal diverticulosis in a 71-year-old female patient. Stomach cancer was diagnosed preoperatively both clinically and by instrumental (endoscopic and radiological) and ...
R.Z. YULDOSHEV, А.А. KHODZHAMKULOV, D.SH. NURALIEV, D.SH. NURALIEV, A.SH. ABDULLOEV   +4 more
doaj   +1 more source

Molecular Characterization of the Human Stomach Microbiota in Gastric Cancer Patients

Frontiers in Cellular and Infection Microbiology, 2017
Helicobacter pylori (Hp) is the primary cause of gastric cancer but we know little of its relative abundance and other microbes in the stomach, especially at the time of gastric cancer diagnosis. Here we characterized the taxonomic and derived functional
G. Yu, J. Torres, N. Hu, R. Medrano-Guzmán, R. Herrera-Goepfert, M. Humphrys, Lemin Wang, Chaoyu Wang, T. Ding, J. Ravel, P. Taylor, C. Abnet, A. Goldstein   +12 more
semanticscholar   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Mathematical modeling and forecasting of esophageal and stomach cancer case rate in Kazakhstan [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2016
Objective. Create a mathematical model and forecast esophageal and stomach cancer case rate in Kazakhstan up to the year 2020. Methods: It is retrospective, descriptive-analytical study.
Galiya Orazova, Leonid Karp, Gulnar Rakhimbekova, Anargul Nogayeva   +3 more
doaj   +1 more source