Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Incidence and mortality of stomach cancer in Shandong Province in 2012
Stomach cancer is common in the Chinese population. The present study aimed to analyze the incidence and mortality as a result of stomach cancer in Shandong Province, in order to provide a reference for cancer prevention and control.
Zhentao Fu+9 more
doaj +1 more source
Metastatic tumors to the stomach: clinical and endoscopic features. [PDF]
AIM: To evaluate the clinical and endoscopic patterns in a large series of patients with metastatic tumors in the stomach. METHODS: A total of 64 patients with gastric metastases from solid malignant tumors were retrospectively examined between 1990 and ...
DE PALMA, GIOVANNI DOMENICO+8 more
core
Theoretical investigation of transgastric and intraductal approaches for ultrasound-based thermal therapy of the pancreas. [PDF]
BackgroundThe goal of this study was to theoretically investigate the feasibility of intraductal and transgastric approaches to ultrasound-based thermal therapy of pancreatic tumors, and to evaluate possible treatment strategies.MethodsThis study ...
Adams, Matthew S+4 more
core +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Attribution of ghrelin to cancer; Attempts to unravel an apparent controversy [PDF]
Ghrelin is an endogenous peptide hormone mainly produced in the stomach. It has been known to regulate energy homeostasis, stimulate secretion of growth hormone, and mediate many other physiologic effects. Various effects attributed to ghrelin contribute
Khani, Leila+5 more
core +1 more source
The role of art-making in identity maintenance: Case studies of people living with cancer [PDF]
The aim of this qualitative research was to understand why some people with cancer take up art as a leisure activity, and how visual art-making in daily life might support identity maintenance/ reconstruction.
Prior, S, Reynolds, F
core +1 more source
Epidemiology characteristics and trends of incidence and morphology of stomach cancer in Iran.
BACKGROUND Stomach cancer is the fourth most common cancer and the second leading cause of cancer- related death through the world. It is predicted that the number of new cancer cases will be more than 15 million cases by 2020.
Zeinab Almasi+2 more
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Association between family history and mismatch repair in colorectal cancer [PDF]
BACKGROUND AND AIMS: Germline mutations in mismatch repair (MMR) genes cause a greatly increased risk of cancer of the gastrointestinal and female reproductive tracts (hereditary non-polyposis colorectal cancer (HNPCC)).
Bell, S.M.+6 more
core +2 more sources