Results 81 to 90 of about 502,113 (333)
Frontiers in Cellular and Infection MicrobiologyBackgroundDuring severe acute pancreatitis (SAP), damage to the intestinal mucosal barrier and translocation of intestinal pathogenic bacteria are key mechanisms that accelerate the disease progression of SAP.
Xiaobin Zhang +16 more
doaj +1 more source
The burden of non communicable diseases in developing countries [PDF]
, 2005 Background: By the dawn of the third millennium, non communicable diseases are sweeping the entire globe, with an increasing trend in developing countries where, the transition imposes more constraints to deal with the double burden of infective and ...
Boutayeb, A, Boutayeb, S
core +3 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Ramadan, the month of fasting [PDF]
, 2008 Socially, fasting is an expression of unity with the poor, the family, and the whole society. This is a period in which the rich have first-hand experience of what it is to be poor, the pains the needy suffers in normal living conditions.
Sahar, Nadima
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Uncovering the Multitarget Therapeutic Mechanism of Tong-Xie-Yao-Fang on Irritable Bowel Syndrome
Journal of Food QualityBackground. This study investigated the pharmacological mechanisms of Tong-Xie-Yao-Fang (TXYF) against irritable bowel syndrome (IBS). Methods. The chemical profile of TXYF was identified through UHPLC-QTOF-MS.
Xiangxue Ma +5 more
doaj +1 more source
Noninvasive ¹³C-octanoic acid breath test shows delayed gastric emptying in patients with amyotrophic lateral sclerosis [PDF]
, 1999 Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive loss of motor neurons. However, ALS has been recognized to also involve non-motor systems.
Folwaczny, Christian +6 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The effect of various drugs on experimentally induced ulcers in immobilized rats [PDF]
Experiments related to the importance of functional disorders in the central nervous system in connection with stomach diseases were performed on Wistar rats.
Schramm, H.
core +1 more source
Cancer incidence in Golestan province: Report of an ongoing population-based cancer registry in Iran between 2004 and 2008 [PDF]
, 2012 Background: Golestan Province, at the western end of the Asian esophageal cancer (EC) belt in northeastern Iran, was reported to have one of the highest worldwide rates of EC in the 1970s.
Aarabi, M. +7 more
core +1 more source