Results 101 to 110 of about 2,156,597 (251)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

CDC's Division of Vector\uc2\uadBorne Diseases

Virtually everyone on earth is vulnerable to diseases from viruses and bacteria transmitted to people through bites of mosquitoes, ticks, fleas, and other insects, known as vectors. West Nile virus, Lyme disease, and Rocky Mountain spotted fever are some

core  

The important practical results and modern lines in studying diseases of the stomach and duodenum (Review of the Seventeenth Russian Gastroenterological Week proceedings, October, 10–12, 2011, Moscow)

, 2012
The aim of review. To analyze and present in brief contents of original materials, The Seventeenth Russian Gastroenterological Week (October, 10–12, 2011, Moscow,) published in the section «Diseases of the stomach and duodenum» (Ros. zhurn..gastroenterol.
A. A. Samsonov, D. N. Andreyev, I. V. Mayev, N. G. Andreyev   +3 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

The effect of proton pump inhibitors in stomach diseases

Кваліфікаційна робота за спеціальністю 226 Фармація, промислова фармація спеціалізація 226.01 Фармація. Керівник: доцент закладу вищої освіти кафедри внутрішньої медицини кандидат медичних наук, Буздуган Інна ОлексіївнаМета дослідження.
Попович, Маріна Вікторівна, Popovych, M. V.   +1 more
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Report of the Advisory Committee on Communicable Diseases in Prison.

, 1993
In 1990 the Minister for Justice announced the establishment of an Advisory Committee on Communicable Diseases in Prisons with the following terms of reference:- "To examine the problems posed by communicable diseases affecting offenders in prisons ...
Advisory Committee on Communicable Diseases in Prison
core  

Years of Life Lost of Patients With Early Adenocarcinoma of the Esophagogastric Junction Compared to Esophageal or Gastric Adenocarcinoma. A Registry-Based Study. [PDF]

Cancer Med
Bollschweiler E, Hölscher AH, Schumacher B, Pech O, Drebber U, in Cooperation with the German Cancer Registry, RKI.   +6 more
europepmc   +1 more source