Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
A 5-year mortality-prediction model for patients with stomach cancer, based on the Korean nationwide health insurance claim database. [PDF]
Medicine (Baltimore)Kim J +5 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Protect yourself from tickborne diseases [PDF]
"Ticks can be found in most of the United States, and many carry serious diseases. Some of the diseases that you can get from a tick bite include: anaplasmosis, babesiosis, Colorado tick fever, ehrlichiosis, Lyme disease, Powassan encephalitis, Q fever ...
core
The Association Between Stomach Disease and Chronic Obstructive Pulmonary Disease: A Cross-Sectional Analysis of the 2018 China Health and Retirement Longitudinal Study (CHARLS). [PDF]
Int J Chron Obstruct Pulmon DisWang H, Sun YZ, Li SY.
europepmc +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Long-Term Oncological Implications of Hormone Replacement Therapy in Women With Hypogonadotropic Hypogonadism: A Propensity-Matched Study. [PDF]
CureusEidbo S +4 more
europepmc +1 more source
The Surgery of the Simple Diseases of the Stomach [PDF]
The Boston Medical and Surgical Journal, 1903 openaire +2 more sources
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Laparoscopic Splenectomy for Sclerosing Angiomatoid Nodular Transformation of the Spleen after a Whipple Procedure: A Case Report. [PDF]
Surg Case RepKato K +11 more
europepmc +1 more source