Results 91 to 100 of about 716,122 (354)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Gastric Schwannoma: A Rare but Important Differential Diagnosis of a Gastric Submucosal Mass

open access: yesCase Reports in Surgery, 2012
Schwannomas are generally slow growing asymptomatic neoplasms that rarely occur in the GI tract. However, if found, the most common site is the stomach.
William Yoon   +5 more
doaj   +1 more source

Metastatic tumors to the stomach: clinical and endoscopic features. [PDF]

open access: yes, 2006
AIM: To evaluate the clinical and endoscopic patterns in a large series of patients with metastatic tumors in the stomach. METHODS: A total of 64 patients with gastric metastases from solid malignant tumors were retrospectively examined between 1990 and ...
DE PALMA, GIOVANNI DOMENICO   +8 more
core  

The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]

open access: yes, 2014
G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin   +8 more
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Seroprevalence of Helicobacter pylori infection among an adult population of Lima, Peru 2017

open access: yesHorizonte Médico, 2017
Objective: To know the seroprevalence of Helicobacter pylori infection among an adult population of Lima, Peru 2017. Materials and methods: Descriptive, prospective, cross-sectional study.
Arturo Pareja Cruz   +2 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Epidemiology and morphology of malignant gastrointestinal tumors in Kabardino-Balkarian Republic for 25 years

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of investigation. To study dynamics of morbidity gastrointestinal tumors in Kabardino-Balkar Republic for 25-year period, to compare to the Russian and world wide epidemiological data. Material and methods. Annual reports of oncological dispensary of
A. A. Tkhakakhov
doaj   +1 more source

Cachexia index and its relationship with resection operability in patients with gastric adenocarcinoma [PDF]

open access: yesJournal of Analytical Research in Clinical Medicine, 2018
Introduction: Gastric cancer is one of the relatively common malignancies all over the world, and is one of major problems of health care system. Nowadays, importance of cachexia is demonstrated in prognosis of various malignancies.
Alireza Barband   +4 more
doaj   +1 more source

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