Stomach metastasis of breast carcinoma mimicking primary gastric neoplasm on fluorodeoxy glucose-positron emission tomography-computed tomography [PDF]
Prathamesh Joshi+4 more
openalex +1 more source
Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer+8 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Cancer: second cause of death among the elderly in Medellín, 2002-2006
Objective: to describe the behavior of lung, stomach, andprostate cancer mortality among the elderly in the city of Medellinfrom 2002 to 2006. Methodology: a descriptive study with asecondary information source.
Luz M. Bustamante A+2 more
doaj
Case analysis of 24 cases of Oxyntic gland neoplasm of the stomach [PDF]
Xinyuan Xie+4 more
openalex +1 more source
Metachronous Multiple Primary Malignant Neoplasms of the Stomach and the Breast: Report of Two Cases With Review of Literature [PDF]
Vilvapathy Senguttuvan Karthikeyan+6 more
openalex +1 more source
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
Stool Microbiota Composition Differs in Patients with Stomach, Colon, and Rectal Neoplasms [PDF]
Omar Youssef+12 more
openalex +1 more source
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
Gastroenteroanastomosis (GEA): Method of choice in the advanced stomach cancer in older age [PDF]
Kocić Miomir+4 more
doaj +1 more source