Results 71 to 80 of about 91,023 (291)

Gastric Schwannoma: A Rare but Important Differential Diagnosis of a Gastric Submucosal Mass

open access: yesCase Reports in Surgery, 2012
Schwannomas are generally slow growing asymptomatic neoplasms that rarely occur in the GI tract. However, if found, the most common site is the stomach.
William Yoon   +5 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Clinicopathological Characteristics of Patients with Gastric Cancer according to the Expression of LIN28A

open access: yesGut and Liver, 2016
Background/AimsAlthough LIN28A is known to potentially play a role in the oncogenesis of various cancers, whether LIN28A expression is a predictor of poor prognosis in patients with gastric cancer has not been fully explored.
Chan Hyuk Park   +4 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Epidemiology of gastric cancer and perspectives for prevention

open access: yesSalud Pública de México, 1997
The most recent estimates of the world-wide incidence of cancer indicate that gastric cancer was in 1990 the second most frequent cancer in the world (after lung cancer), with about 900 000 new cases diagnosed every year.
MUÑOZ NUBIA, FRANCESCHI SILVIA
doaj  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Some correlations between eight types of malignant neoplasms: A hint from cancer dynamics of 31 European countries in 20 years [PDF]

open access: yesNetwork Biology, 2017
In present study, the data of standardised death rates of malignant neoplasms per 100000 inhabitants in 31 European countries during 1994-2013 were used to analyze linear correlations between eight types of cancers in terms of induced death rates.
WenJun Zhang
doaj  

Risk Factors for Gastric Tumorigenesis in Underlying Gastric Mucosal Atrophy

open access: yesGut and Liver, 2017
Background/AimsAtrophic gastritis is considered a premalignant lesion. We aimed to evaluate the risk factors for gastric tumorigenesis in underlying mucosal atrophy.Methods : A total of 10,185 subjects who underwent upper gastrointestinal endoscopy ...
Ji Hyun Song   +4 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Gastrointestinal stroma tumor of the stomach

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
The gastrointestinal stroma tumor is an infrequent type of tumor of mesenchymal origin called sarcoma. It appears in the wall of the digestive lobe, the stomach, the small intestine, the colon, the esophagus and occasionally in the omentum, mesenteric ...
Jaime Landell Cruz   +1 more
doaj  

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