Results 101 to 110 of about 253,827 (253)

Effects of two intravenouse dose levels of omeprazole on the gastric juice pH of healthy horses

Revista Colombiana de Ciencias Pecuarias
Summary Background: omeprazole suppresses gastric acid secretion and increases gastric juice pH by blocking the H+, K+ ATPase in the secretory membrane of parietal cells.
Jhon D Ruiz, Juan E Ramírez, Ángel Lezcano   +2 more
doaj   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

The stress ulcer syndrome [PDF]

, 1986
The stress ulcer syndrome is described in this thesis. This syndrome is seen in patients admitted to intensive care departments or being treated in field hospitals, in disaster areas, or battle fields. Acute mucosal lesions associated with burns (Curling'
Essen, H.A. van
core   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Attenuation of indomethacin-induced gastric ulceration by methanolic extract of Cucumis Melo (L. indorous) seeds in male Wistar rats

African Scientific Reports
Inflammatory markers has been implicated during NSAID-induced gastric ulcer as it enhances leukocyte adhesion which also contribute to lipid peroxidation and decrease in antioxidants. Cucumis melo seeds (L. Indorous) is well known to contain some active
Grace Adebayo-Gege, James Adiwu, Abednego Ovey Angbashim, Toyin Dorcas Alabi, Murtala Ngabea Audu , Frank Abimbola Ogundolie   +5 more
doaj   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

A Large Stomach Ulcer Is Associated With Raised Mortality in a Cohort of Patients Who Underwent Open Repair of Perforated Peptic Ulcer: A Five-Year Follow-Up Study. [PDF]

Cureus, 2020
Aljiffry M, Alshehrani EA, Saeed A, Albugmi F, Alsulami I, Alzahrani W, Al-Radi OO, Alzahrani AH.   +7 more
europepmc   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

Advanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song, Zhewei Shuai, Weiyan Sun, Liang Chen, Yiwei Shen, Jiateng Hu, Yuanqi Ma, Jie Luo, Meilin Huang, Yan Luo, Yunlang She, Guangdong Zhou, Chang Chen, Dong Lei   +13 more
wiley   +1 more source

The role of Helicobacter pylori in normal microbiocenosis and dysbacteriosis of mucous microflora of the esophagogastroduodenal zone in its inflammation, erosion and ulcer

Терапевтический архив, 2012
Aim. To determine a population level and significance of Helicobacter pylori in normal microbiocenosis and dysbiosis of mucosal microflora in the esophagogastroduodenal zone. Material and methods.
Vyacheslav Vasil'evich Chernin, Viktor Mikhaylovich Bondarenko, Vyacheslav Mikhaylovich Chervinets, Sergey Nikolaevich Bazlov, V V Chernin, V M Bondarenko, V M Chervinets, S N Bazlov   +7 more
doaj