Results 51 to 60 of about 9,142,015 (290)

Subgroup analyses for comparison of stone-free rate between Microperc and RIRS in adult patients.

open access: yes, 2018
Subgroup analyses for comparison of stone-free rate between Microperc and RIRS in adult patients.
Zhijian Zhao (389825)   +7 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Predictors of Success for Stone Fragmentation and Stone-Free Rate After Extracorporeal Shockwave Lithotripsy in the Treatment of Upper Urinary Tract Stones

open access: yesUrology Journal, 2012
PURPOSE: To evaluate factors affecting the success rate of stone fragmentation and stone-free rate after extracorporeal shockwave lithotripsy (SWL) in treatment of upper urinary tract stones.
Kiyoshi Takahara   +5 more
doaj  

A calibration plot of the Seoul National University Renal Stone Complexity (S-ReSC) score to predict the stone-free rate after single-tract percutaneous nephrolithotomy.

open access: yes, 2013
A calibration plot of the Seoul National University Renal Stone Complexity (S-ReSC) score to predict the stone-free rate after single-tract percutaneous nephrolithotomy.
Sung Kyu Hong (423172)   +8 more
core   +1 more source

Stone free rate assessment after percutaneous nephrolithotomy using nephrolitometric nomogram

open access: yesCirugía y Cirujanos (English Edition), 2017
Percutaneous nephrolithotomy remains the standard of care for kidney stones larger than 2cm. Therefore, setting a prognosis for complete stone resolution through this method is essential. The prognostic tools available have limited prediction.To evaluate the stone-free rate in patients undergoing percutaneous nephrolithotomy with the Clinical Research ...
Jason Damián, Landa-Salas   +5 more
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Percutaneous Stone Surgery in Spina Bifida Patients––Are Stone-Free Rates Worth the Risk? [PDF]

open access: yesJournal of Endourology, 2017
Percutaneous stone surgery can be challenging in spina bifida (SB) patients due to their body habitus and spinal cord anomalies. A safe surgical approach may necessitate acceptance of lower stone-free (SF) rates. We seek to determine if anatomic complexity, as measured by spinal cord curvature and torso length, is associated with SF rates after ...
Rajeev, Chaudhry   +5 more
openaire   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Impact of Preoperative Ureteral Stenting in Retrograde Intrarenal Surgery for Urolithiasis

open access: yesMedicina, 2023
Background and Objectives: Ureteral stent insertion passively dilates the ureter. Therefore, it is sometimes used preoperatively before flexible ureterorenoscopy to make the ureter more accessible and facilitate urolithiasis passage, especially when ...
Jae Yong Jeong   +6 more
doaj   +1 more source

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