Results 61 to 70 of about 9,142,015 (290)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Stone-Free Rate and Complications Rate of Mini-Percutaneous Nephrolithotomy for Stag-Horn Stones

Indus Journal of Bioscience Research
Introduction: Staghorn calculi are complicated stones of the kidney, which are associated with infection and kidney deterioration. Mini-percutaneous nephrolithotomy (mini-PCNL) provides an alternative to standard PCNL that is less invasive with a possible high stone-free rates (SFR) and reduced complications.
Ajmal Khan, Mujahid Ali Khoso, null Muhammad Tahir, null Aman Ullah, Farhaad Khan Tareen, Ajmal Khan Jogezai   +5 more
openaire   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Determining the Stone Free Rate of Retrograde Intrarenal Surgery. Which Radiological Technique? RIRSearch Study Group [PDF]

OBJECTIVE To evaluate the sensitivity and specificity of ultrasonography (USG) and kidney ureter bladder radiography (KUB) for the determination of stone-free status of retrograde intrarenal surgery (RIRS) according to different stone-free status ...
Ozman, Oktay, Sancak, Eyüp Burak, Çakır, Hakan, Sıddıkoğlu, Duygu, Yazıcı, Cenk Murat, Gönen Korcan, Aysun, Başataç, Cem, Akgül, Hacı Murat, Çınar, Önder, Gonen, Korcan Aysun, Dayısoylu, Hulusi Sıtkı, Cinar, Onder, Akgul, Haci Murat, ÖNAL, BÜLENT, Baseskioglu, Barbaros, Cakir, Hakan, Siddikoglu, Duygu, Akpinar, Haluk, Yazici, Cenk Murat   +18 more
core   +2 more sources

High‐Entropy Alloy Interlayers Toward Advanced Joining for High‐Performance Structural Applications: Current Progress and Emerging Challenges

Advanced Engineering Materials, EarlyView.
HEA interlayers offer a versatile route for joining high‐performance structural materials. Their compositional and structural design regulates interfacial reactions, suppresses brittle IMCs, and improves metallurgical bonding. Sandwich interlayers further integrate defect healing with precipitation strengthening, enabling improved strength–ductility ...
Lin Yuan, Jiafen Song, Jinglong Li, Jiangtao Xiong, Tao Yang   +4 more
wiley   +1 more source

Single-session ureteroscopic pneumatic lithotripsy for the management of bilateral ureteric stones

International Brazilian Journal of Urology, 2012
PURPOSE: In nowadays there is no consensus on single-session ureteroscopic lithotripsy (URSL) for the management of bilateral ureteric stones. The aim of this study was to evaluate efficacy and safety of single-session URSL in patients with bilateral ...
Kenan Isen
doaj   +1 more source

Percutaneous Nephrolithotomy for Paediatric Stone Disease [PDF]

, 2015
We evaluated the outcomes and complications occurring following percutaneous nephrolithotomy (PCNL) procedures performed in paediatric patients. There were 291 paediatric patients (293 renal units) included in the current study and who underwent PCNL in ...
İbrahim Topcu, Ahmet Çamtosun, Ramazan Altıntaş, Ali Güneş, Hüseyin Çelik, Cemal Taşdemir, Serhan Çimen   +6 more
core  

A New Scoring System for Predicting Stone-free Rate After Retrograde Intrarenal Surgery: The "Resorlu-Unsal Stone Score"

, 2012
OBJECTIVE To investigate the prognostic factors associated with the treatment efficacy of retrograde intrarenal surgery (RIRS) and develop a scoring system for predicting the stone-free rate after this ...
Unsal, ALİ, Oztuna, Derya, Gulec, Handan, Resorlu, Berkan, Oztuna, D, Resorlu, B, Unsal, A   +6 more
core   +1 more source