Results 41 to 50 of about 2,416,469 (290)

Hacı Bayram Veli’nin Şiirlerinde İnsanın İkilemi

open access: yesTasavvuf İlmi ve Akademik Araştırma Dergisi, 2023
Anadolu tasavvuf geleneğinde günümüzde yadsınamaz derecede önem taşıyan şahsiyetlerden biri de Hacı Bayram Veli’dir. Tasavvufi kurum ve ekoller açısından farklı akisleri olan Hacı Bayram Veli’nin Türk toplumunun ürettiği farklı kültürel enstrümanlarda da
Musa Kaval
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Gritty sensation on catheter: A new clinical sign for self-diagnosis of stone formation in the continent urinary pouch

open access: yesIndian Journal of Urology, 2010
With more experience and better management, the incidence of complications like stone formation after continent urinary diversion is uncommon today.
Apul Goel   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Analyses of Urban Pavement Surface Temperatures

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2015
Heat islands are areas that have higher air temperatures than their surroundings. It has been proven that the use of certain types of pavement surface materials contributes to the occurrence of heat islands.
Aleksandra Deluka-Tibljaš   +3 more
doaj   +1 more source

The association between single nucleotide polymorphism in vitamin D receptor and calcium oxalate urolithiasis in dogs

open access: yesJournal of Veterinary Internal Medicine, 2021
Background Polymorphisms of the vitamin D receptor (VDR) are associated with calcium oxalate (CaOx) nephrolithiasis in humans. Objectives To investigate the association between VDR polymorphisms and susceptibility to CaOx urolithiasis in dogs.
Sumonwan Chamsuwan   +4 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The relevance of Randall′s plaques

open access: yesIndian Journal of Urology, 2014
The pathophysiology of nephrolithiasis is not fully understood. The pioneering work of Alexander Randall in the 1940s sought to clarify our understanding of stone formation.
Ruth Strakosha   +2 more
doaj   +1 more source

English Studies as a Site for Healing: A Conversation about Place-Based and Indigenous Pedagogies in the English Classroom [PDF]

open access: yes, 2017
This article summarizes a roundtable discussion from the 2016 Alaska Native Studies Conference among professors and students from two English Studies courses at the University of Alaska Anchorage: History of the English Language and History of Rhetoric ...
Brook Adams, Heather   +5 more
core  

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