Results 191 to 200 of about 2,074,633 (250)

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

open access: yesAdvanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng   +7 more
wiley   +1 more source

Molecular Signatures of HIV‐Induced Neuroinflammation and Neurodegeneration in Human Cerebral Organoids: Identification of Therapeutic Targets for NeuroHIV

open access: yesAdvanced Science, EarlyView.
HIV preferentially infects microglia, activating IL‐17A‐driven IFN‐γ/STAT1, CEBPB, and NF‐κB signaling that converges with cGAS‐STING and Notch–NEURL1 pathways, promoting neuroinflammation, mitochondrial dysfunction, and synaptic impairment. cART suppresses viral replication, attenuates inflammatory signaling, and at least partially restores ...
Karthick Chennakesavan   +7 more
wiley   +1 more source

In Situ CO2‐Induced Hydrogels for Enhancing Carbon Sequestration in Saline Aquifers

open access: yesAdvanced Science, EarlyView.
A novel integrated method that combines in situ CO2‐induced phase‐transition hydrogels formed by a C22‐tailed tertiary amine dispersion with tailored deep eutectic solvents to increase CO2 sequestration in saline aquifers. ABSTRACT Carbon sequestration in saline aquifers underpins global net‑zero emission goals, yet existing CO2 storage capacity ...
Fuchuan Liu   +5 more
wiley   +1 more source

Impact of operative time on complications after PCNL in the elderly (aged ≥70 years): the Safety and Efficacy of Nephrolithotomy in Older patients undergoing PCNL (SENIOR-PCNL) study. [PDF]

open access: yesBJU Int
Nowak Ł   +41 more
europepmc   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

open access: yesAdvanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan   +14 more
wiley   +1 more source

Confronting complexity: toward equitable healthcare technology design and evaluation for socioeconomically marginalized patients. [PDF]

open access: yesJAMIA Open
Veinot TC   +8 more
europepmc   +1 more source

Metal–Phenolic Complexation Governs Soil Mineral Crystallinity to Enhance Crop Growth

open access: yesAdvanced Science, EarlyView.
A coordination‐driven, coprecipitation approach is presented to obtain polyphenolic‐incorporated minerals with tunable crystallinity, offering insights into how plants may influence soil mineral structures. Soil minerals can incorporate polyphenolic secondary metabolites and enhance plant nutrition by facilitating the formation of amorphous metal ...
Jong‐Rok Jeon   +10 more
wiley   +1 more source

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