Results 211 to 220 of about 2,074,633 (250)

Mode‐Resolved Phonon Dynamics Under Chemical Pressure in SnTe Thermoelectrics

open access: yesAdvanced Science, EarlyView.
Chemical pressure reshapes low‐energy optical phonons in SnTe, altering their dispersion and scattering with heat‐carrying acoustic modes. Positive and negative pressure states modify phonon frequencies and lifetimes in distinct ways, revealing how mode‐selective lattice perturbations regulate acoustic–optical interactions and suppress lattice thermal ...
Zhihao Li   +7 more
wiley   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

open access: yesAdvanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo   +15 more
wiley   +1 more source

LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening

open access: yesAdvanced Science, EarlyView.
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico   +7 more
wiley   +1 more source

One‐Step Induction of Oogonia‐Like and Pro‐Spermatogonia‐Like Cells From Porcine Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He   +14 more
wiley   +1 more source

Habitat‐Specific Design Strategies for Untethered Soft Robots

open access: yesAdvanced Science, EarlyView.
Habitat shapes the design of untethered soft robots. Across land, water, air, and living tissues, environmental constraints govern viable combinations of compliant structures, actuation mechanisms, and energy delivery. This review connects these constraints with robotic performance and identifies design principles for advancing adaptable, durable, and ...
Siyang Li   +3 more
wiley   +1 more source

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