Results 221 to 230 of about 2,074,633 (250)

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao, Long He, Yu Lu, Zanglong Deng, Hongzhen Wei, Yunpeng Zhang, Ming Yang, Tao Yin   +7 more
wiley   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

Advanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun, Shuangyang Li, Zhixu He, Jingyi Xie, Yaxian Luo, Xuankai Fan, Jingyu Zhang, Luying Qin, Lianjie Peng, Tao Qiu, Tian Zhang, Huiming Wang, Mengfei Yu   +12 more
wiley   +1 more source

CLINICAL PREDICTORS OF CHOLEDOCHOLITHIASIS IN MILD ACUTE BILIARY PANCREATITIS: DEVELOPMENT OF AN EXPLORATORY RISK STRATIFICATION MODEL. [PDF]

Arq Gastroenterol
Zacharias BL, Macedo GC, Antunes PSL, Andrade VA, Perlingeiro JGA, Assef JC.   +5 more
europepmc   +1 more source

The Efficacy of a Home Monitoring App for Children With Medical Complexity: Protocol for a Randomized Controlled Trial. [PDF]

JMIR Res Protoc
Nkoy F, Stone B, Foster C, Zhu A, McCormick S, Wheeler M, Walsh P, Karwowski C, East S, Sward K, Sheng X, Reynolds C, Poll JB, Murphy N.   +13 more
europepmc   +1 more source

Artificial intelligence versus classical scoring systems: a comparative analysis of stone-free prediction after percutaneous nephrolithotomy. [PDF]

Urolithiasis
Elmaağaç B, Özercan AY, Gölbaşı A, Biçer H, Arslan E, Karadağ MA.   +5 more
europepmc   +1 more source

Silicosis from dry-cutting engineered stone in the fabrication of countertops. [PDF]

CMAJ
Yuen M, Ho K, Abdelsayad A, Lau A, Tarlo SM.   +4 more
europepmc   +1 more source

Clinical heterogeneity mapping and machine learning-based prediction of recurrence in gallstone disease: a retrospective cohort study of 9,939 patients. [PDF]

PeerJ
Zheng X, Yan Y, Bian C, Sun X, Bai X, Zhuang X, Zhang Y.   +6 more
europepmc   +1 more source