Results 41 to 50 of about 1,597,779 (302)

Constant dripping wears away a stone: Fatigue damage causing particles' cracking

open access: yes, 2019
Constant dripping wears away a stone: Fatigue damage causing particles ...
He, Haiyong   +6 more
core   +1 more source

The food niche overlap of five fish species in the Úpoř brook (Central Bohemia)

open access: yesKnowledge and Management of Aquatic Ecosystems, 2013
The diet and food niche overlap of five fish species in the Úpoř brook was evaluated. The supply of food represented by benthos was studied, and the proportion of total food particles in the intestine of brown trout Salmo trutta L ...
Vlach P., Švátora M., Dušek J.
doaj   +1 more source

Feed particle selection and nutrient intake altered by pecking stone consumption and beak length in free-range laying hens

open access: yesAnimal Nutrition, 2019
The present study investigated the effects of pecking stones on feeding behaviour of hens from 16 to 46 weeks of age. Eighteen flocks of Hy-Line Brown hens were housed in 2 commercial free-range housing systems.
Zafar Iqbal   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Effect of calcium lignosulfonate on the deformation and failure characteristics of cementing stone and its modification mechanism

open access: yesMeitan xuebao, 2023
In the coalbed methane extraction of surface wells in the mining area, the mining of coal seam in working face will cause a significant disturbance to overlying rock layer, which in turn will lead to the deformation and damage of surface wells.
Quanle ZOU   +4 more
doaj   +1 more source

Physico-chemical stone-mortar compatibility of commercial stone-repair mortars of historic buildings from Paris

open access: yes, 2016
International audiencehe physico-chemical compatibility of the most frequently used commercial stone-repair mortars applied to repair surface damage of a common limestone (Euville stone) employed in the basements of historic buildings from Paris was ...
Tagnit-Hammou, M.   +12 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Physico-Chemical Substantiation of Obtaining an Effective Cement Composite with Ultrafine GGBS Admixture

open access: yesBuildings, 2023
To solve a number of problems in construction materials science, composites with nano and ultrafine admixtures were analyzed. Their properties were studied, taking into account the variants of homogenization and stabilization of the system.
Irina Kozlova   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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